INT170856

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Context Info
Confidence 0.35
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (IFI27) molecular_function (IFI27)
IFI27 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 1 18.12 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 43 99.46 Very High Very High Very High
Cancer 62 88.28 High High
Rheumatoid Arthritis 3 84.76 Quite High
Infection 68 76.32 Quite High
Dermatological Disease 1 73.20 Quite High
Retinoblastoma 2 64.00 Quite High
Metastasis 11 62.48 Quite High
Viral Infection 2 55.60 Quite High
Stress Incontinence 32 50.00 Quite Low
Adenocarcinoma 11 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Purified mouse monoclonal antibody to p27 cell cycle inhibitor protein, clone G173-524, was purchased from PharMingen, San Diego, CA, and used at dilution 1:50.
p27 Binding (used) of
1) Confidence 0.35 Published 2001 Journal BMC Clin Pathol Section Body Doc Link PMC59662 Disease Relevance 0.06 Pain Relevance 0
In the present study, we did not find any significant association between p27, cyclin D1 and proliferative activity.
p27 Neg (not) Binding (association) of
2) Confidence 0.34 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1208869 Disease Relevance 0.49 Pain Relevance 0
This includes three induced by DMSO (Akt, p27, PTEN) and seven by ATRA (RXR-?
p27 Binding (seven) of
3) Confidence 0.17 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2791157 Disease Relevance 0.24 Pain Relevance 0
However, because of the staining pattern of this antibody (punctuate, with a fuzzy staining of the whole cell cytoplasm), subsequent double staining procedures were performed using an antibody to HIV-1 p24 capsid protein that crossreacts with SIV p27.
p27 Binding (crossreacts) of associated with acquired immune deficiency syndrome or hiv infection
4) Confidence 0.05 Published 2007 Journal Retrovirology Section Body Doc Link PMC1805449 Disease Relevance 0.35 Pain Relevance 0

General Comments

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