INT170886

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Context Info
Confidence 0.49
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 4.63
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

histone binding (AIRE) nucleolus (AIRE) plasma membrane (AIRE)
nucleus (AIRE) DNA binding (AIRE) cytoplasm (AIRE)
Anatomy Link Frequency
Thyroid 1
AIRE (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 100.00 Very High Very High Very High
imagery 10 76.80 Quite High
rheumatoid arthritis 2 75.04 Quite High
Chronic pancreatitis 4 62.24 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 54 100.00 Very High Very High Very High
Cystic Fibrosis 1 100.00 Very High Very High Very High
Premature Ovarian Failure 12 99.76 Very High Very High Very High
Diabetes Mellitus 10 99.68 Very High Very High Very High
Iron Overload 1 99.12 Very High Very High Very High
Disease 98 98.24 Very High Very High Very High
Premature Menopause 2 98.20 Very High Very High Very High
Pernicious Anemia 6 98.16 Very High Very High Very High
Graves' Ophthalmopathy 2 98.06 Very High Very High Very High
Hyperthyroidism 2 97.78 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several forms of POF are not of autoimmune etiology, however in a majority of our patients with premature menopause other autoimmune disorders have been observed.
Gene_expression (etiology) of autoimmune associated with premature menopause, autoimmune disease and premature ovarian failure
1) Confidence 0.49 Published 2010 Journal Autoimmune Diseases Section Body Doc Link PMC3005832 Disease Relevance 1.76 Pain Relevance 0
Thyroid abnormalities, especially hypothyroidism and thyrotoxicosis due to Graves' disease or Hashitoxicosis, as well as insulin dependent diabetes mellitus (T1DM) were dominant autoimmune disorders.
Gene_expression (disorders) of autoimmune in Thyroid associated with autoimmune disease, diabetes mellitus, congenital anomalies, graves' ophthalmopathy, thyroid disease, hyperthyroidism and disease
2) Confidence 0.49 Published 2010 Journal Autoimmune Diseases Section Body Doc Link PMC3005832 Disease Relevance 2.40 Pain Relevance 0.08
This technique was initially used for identifying single nucleotide polymorphisms on the Y chromosome [9] and, thereafter, has been emerging as a sensitive, rapid, low-cost, and reliable method for mutation detection and screening in different genes, including the cystic fibrosis transmembrane conductance regulator gene [10], the hereditary hemochromatosis gene [11], and the BRCA1 and BRCA2 genes [12].
Gene_expression (detection) of regulator gene associated with fibrosis, cystic fibrosis and iron overload
3) Confidence 0.01 Published 2001 Journal BMC Genet Section Body Doc Link PMC60523 Disease Relevance 0.47 Pain Relevance 0.11

General Comments

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