INT170910

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Context Info
Confidence 0.00
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pcbd1, Mapk8) nucleus (Pcbd1, Mapk8) mitochondrion (Mapk8)
lyase activity (Pcbd1) cytosol (Mapk8) signal transduction (Mapk8)
Anatomy Link Frequency
neuronal 3
Pcbd1 (Rattus norvegicus)
Mapk8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 1 52.76 Quite High
agonist 23 50.00 Quite Low
cINOD 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 90.84 High High
Death 13 65.40 Quite High
Apoptosis 8 44.28 Quite Low
Toxicity 5 36.32 Quite Low
Lymphatic System Cancer 1 32.40 Quite Low
Atherosclerosis 11 13.44 Low Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During growth factor deprivation induced PCD in neuronal PC12 cells, there is a sustained activation of the JNK and p38 pathways while the activities of ERK pathway is inhibited.
Negative_regulation (deprivation) of PCD in neuronal Positive_regulation (induced) of Positive_regulation (activation) of JNK in neuronal
1) Confidence 0.00 Published 2001 Journal BMC Pharmacol Section Body Doc Link PMC60650 Disease Relevance 0.21 Pain Relevance 0.03

General Comments

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