INT170981

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2001
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.62
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL5) extracellular region (IL5)
Anatomy Link Frequency
internal 2
IL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 164 94.96 High High
cytokine 98 83.92 Quite High
fibrosis 6 74.80 Quite High
Inflammatory response 7 68.04 Quite High
chemokine 32 52.16 Quite High
antagonist 34 5.00 Very Low Very Low Very Low
agonist 20 5.00 Very Low Very Low Very Low
corticosteroid 7 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 447 99.18 Very High Very High Very High
INFLAMMATION 174 94.96 High High
Metaplasia 6 77.20 Quite High
Fibrosis 4 74.80 Quite High
Eosinophilia 21 63.08 Quite High
Death 3 57.52 Quite High
Occupational Lung Diseases 39 56.64 Quite High
Pulmonary Disease 6 50.08 Quite High
Pneumonia 8 45.04 Quite Low
Disease 31 42.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B, but this does not account for all effects, as IL-10 is very effective at inhibiting IL-5 transcription, which is independent of NF-?
Neg (independent) Positive_regulation (independent) of Transcription (transcription) of IL-5
1) Confidence 0.10 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 1.13 Pain Relevance 0.29
In fact, greater number of activated eosinophils was seen in the airways <2 mm internal diameter than in the airways >2 mm internal diameter, suggesting that similar but more severe inflammatory process is present in the distal airways.[26] In the same cohort of patients, we have also shown increased IL-5 and IL-4 mRNA-positive cells in the distal airways of asthmatic subjects compared to non-asthmatic controls,[12] and more importantly, the expression of IL-5 mRNA was increased in the distal airways compared to the large airways.[12] Numbers of cells expressing IL-2 and IFN-?
Positive_regulation (increased) of Transcription (expression) of IL-5 in internal associated with asthma and inflammation
2) Confidence 0.06 Published 2007 Journal Annals of Thoracic Medicine Section Body Doc Link PMC2732069 Disease Relevance 0.92 Pain Relevance 0.11
More importantly, the expression of IL-5 mRNA was increased in the small airways compared with the large airways (Fig. 4) [5].
Positive_regulation (increased) of Transcription (expression) of IL-5
3) Confidence 0.04 Published 2001 Journal Respir Res Section Body Doc Link PMC64806 Disease Relevance 0.56 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox