INT17099

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Context Info
Confidence 0.44
First Reported 1985
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 5.50
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GPT) small molecule metabolic process (GPT) biosynthetic process (GPT)
cellular nitrogen compound metabolic process (GPT) cytoplasm (GPT)
Anatomy Link Frequency
liver 2
Blood 1
white blood cell 1
GPT (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 97.92 Very High Very High Very High
headache 4 94.80 High High
nud 1 94.28 High High
anesthesia 4 93.56 High High
depression 1 90.40 High High
Pain 6 88.04 High High
abdominal pain 1 87.64 High High
halothane 2 82.88 Quite High
palliative 1 73.12 Quite High
Paracetamol 3 50.00 Quite Low
Disease Link Frequency Relevance Heat
Immunization 56 100.00 Very High Very High Very High
Fever 5 99.72 Very High Very High Very High
Appetite Loss 2 99.32 Very High Very High Very High
Dyspnea 1 99.24 Very High Very High Very High
Vomiting 4 98.92 Very High Very High Very High
Thrombocytopenia 1 98.60 Very High Very High Very High
Leukopenia 1 98.16 Very High Very High Very High
Anaemia 1 97.92 Very High Very High Very High
Angina 1 97.92 Very High Very High Very High
Headache 4 94.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blood was collected at screening, on immunization days, 7 and 14 days after each immunization and on study days 90, 180, 272 and 364 to determine complete blood count, alanine aminotransferase (ALT) and serum creatinine.
Regulation (collected) of alanine aminotransferase in Blood associated with immunization
1) Confidence 0.44 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2186380 Disease Relevance 1.48 Pain Relevance 0.24
Minor and reversible elevations in the values of GOT, GPT, LDH and bilirubin were noted without the organic change of the liver in beagles after the inhalation exposure to 1.8 MAC of each anesthetic.
Regulation (values) of GPT in liver
2) Confidence 0.26 Published 1991 Journal Masui Section Abstract Doc Link 1875535 Disease Relevance 0.08 Pain Relevance 0.17
A temporary change in the liver functional data (GOT, GPT) was noted in 3 patients.
Regulation (change) of GPT in liver
3) Confidence 0.26 Published 1988 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 3137887 Disease Relevance 0.81 Pain Relevance 0.10
No abnormal laboratory findings were observed except for elevation in GOT and GPT values in 1 case (4.0%), which returned to normal after NFLX treatment.
Neg (except) Regulation (values) of GPT
4) Confidence 0.26 Published 1985 Journal Hinyokika Kiyo Section Abstract Doc Link 4083223 Disease Relevance 1.12 Pain Relevance 0.14
GOT, GPT and LDH values were 242 Ku, 326 Ku and 901 Wu, respectively and peaked at 520 Ku, 709 Ku and 1000 Wu 12-16 days after the operation.
Regulation (values) of GPT
5) Confidence 0.26 Published 1993 Journal Masui Section Abstract Doc Link 8320810 Disease Relevance 0.70 Pain Relevance 0.26
Pertinent clinicopathologic findings were normocytic normochromic anemia, leukopenia, and thrombocytopenia; high serum concentrations of total bilirubin and glucose, low serum concentrations of albumin and potassium, high serum alanine transaminase activity; and, bilirubinuria.
Regulation (concentrations) of alanine transaminase associated with anaemia, leukopenia and thrombocytopenia
6) Confidence 0.04 Published 1994 Journal J. Am. Vet. Med. Assoc. Section Abstract Doc Link 7961073 Disease Relevance 0.84 Pain Relevance 0.12
Current tobacco use was independently associated with high peak values of alanine transaminase and the international normalized ratio.
Regulation (values) of alanine transaminase
7) Confidence 0.04 Published 2003 Journal Aliment. Pharmacol. Ther. Section Body Doc Link 14616163 Disease Relevance 0.06 Pain Relevance 0
Secondary measures included changes in serum biological markers (alkaline phosphatase, alanine transaminase, aspartate transaminase, and gamma-glutamyltransferase), craving, and psychosocial functioning.
Regulation (changes) of alanine transaminase
8) Confidence 0.01 Published 2004 Journal Alcohol. Clin. Exp. Res. Section Body Doc Link 15547458 Disease Relevance 0 Pain Relevance 0
Laboratory test results included white blood cell count, 14.4 x 10(9)/mm3; hemoglobin, 8.5 g/dL; platelets, 1,483,000; and normal values for lipase, amylase, aspartate transaminase, and alanine transaminase.
Regulation (values) of alanine transaminase in white blood cell
9) Confidence 0.00 Published 2003 Journal J. Pediatr. Surg. Section Abstract Doc Link 12677588 Disease Relevance 0.41 Pain Relevance 0.18

General Comments

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