INT171015

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Context Info
Confidence 0.42
First Reported 2002
Last Reported 2007
Negated 0
Speculated 3
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.63
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL5) aging (CCL5) extracellular region (CCL5)
cell-cell signaling (CCL5) cytoplasm (CCL5)
Anatomy Link Frequency
peritoneal fluid 3
macrophages 1
mast cells 1
T cells 1
CCL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 255 100.00 Very High Very High Very High
chemokine 82 100.00 Very High Very High Very High
endometriosis 504 99.96 Very High Very High Very High
substance P 63 93.88 High High
Arthritis 50 91.04 High High
methotrexate 14 89.72 High High
dexamethasone 7 81.76 Quite High
Nerve growth factor 48 81.60 Quite High
metalloproteinase 42 80.60 Quite High
cytokine 126 73.28 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 274 100.00 Very High Very High Very High
Endometriosis 672 99.96 Very High Very High Very High
Necrosis 10 97.20 Very High Very High Very High
Cancer 13 96.84 Very High Very High Very High
Asthma 41 94.08 High High
Hypersensitivity 6 93.68 High High
Adhesions 48 92.80 High High
Juvenile Chronic Polyarthritis 40 91.04 High High
Disease 87 73.60 Quite High
Choristoma 15 63.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Levels of mRNA of the three inflammatory chemokines CCL5 (RANTES), CCL3 (MIP-1?)
Positive_regulation (inflammatory) of Positive_regulation (chemokines) of RANTES associated with chemokine and inflammation
1) Confidence 0.42 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526593 Disease Relevance 0.69 Pain Relevance 0.43
Several studies have demonstrated that human ASM cells are also capable of expressing and secreting biologically active RANTES following stimulation with TNF-?
Positive_regulation (active) of Positive_regulation (stimulation) of RANTES
2) Confidence 0.16 Published 2002 Journal Respir Res Section Body Doc Link PMC64809 Disease Relevance 0.59 Pain Relevance 0.32
In endometriosis, elevated levels of M-CSF, MCP-1, RANTES, and SCF in peritoneal fluid might lead to increased numbers of macrophages, T cells, and mast cells.
Spec (might) Positive_regulation (lead) of in mast cells Positive_regulation (elevated) of RANTES in peritoneal fluid associated with endometriosis
3) Confidence 0.06 Published 2007 Journal Semin Immunopathol Section Body Doc Link PMC2668599 Disease Relevance 0.79 Pain Relevance 0.25
In endometriosis, elevated levels of M-CSF, MCP-1, RANTES, and SCF in peritoneal fluid might lead to increased numbers of macrophages, T cells, and mast cells.
Spec (might) Positive_regulation (lead) of in T cells Positive_regulation (elevated) of RANTES in peritoneal fluid associated with endometriosis
4) Confidence 0.02 Published 2007 Journal Semin Immunopathol Section Body Doc Link PMC2668599 Disease Relevance 0.79 Pain Relevance 0.25
In endometriosis, elevated levels of M-CSF, MCP-1, RANTES, and SCF in peritoneal fluid might lead to increased numbers of macrophages, T cells, and mast cells.
Spec (might) Positive_regulation (lead) of in macrophages Positive_regulation (elevated) of RANTES in peritoneal fluid associated with endometriosis
5) Confidence 0.02 Published 2007 Journal Semin Immunopathol Section Body Doc Link PMC2668599 Disease Relevance 0.79 Pain Relevance 0.25

General Comments

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