INT171018

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Context Info
Confidence 0.18
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.78
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL11) extracellular space (CCL11) extracellular region (CCL11)
cell adhesion (CCL11) cytoskeleton organization (CCL11)
CCL11 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 8 99.78 Very High Very High Very High
cytokine 135 92.76 High High
Inflammation 187 88.24 High High
chemokine 52 86.48 High High
bradykinin 2 24.16 Low Low
antagonist 41 5.00 Very Low Very Low Very Low
agonist 23 5.00 Very Low Very Low Very Low
Inflammatory mediators 12 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 356 92.32 High High
INFLAMMATION 214 88.24 High High
Hypersensitivity 12 69.52 Quite High
Sprains And Strains 1 68.44 Quite High
Targeted Disruption 20 31.44 Quite Low
Eosinophilia 22 5.00 Very Low Very Low Very Low
Disease 22 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 18 5.00 Very Low Very Low Very Low
Airway Remodeling 15 5.00 Very Low Very Low Very Low
Adhesions 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, the BTPs show inhibition of IL-4, IL-5, IL-8, and CCL11 production [150,151].
Negative_regulation (inhibition) of Gene_expression (production) of CCL11
1) Confidence 0.18 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.28 Pain Relevance 0.16
Neither dexamethasone nor IL-10 inhibited the expression of mRNA encoding eotaxin, although IL-10 did inhibit the release of eotaxin protein into the culture medium, suggesting inhibition at a translational and/or post-translational level [32].


Negative_regulation (inhibited) of Gene_expression (expression) of eotaxin associated with dexamethasone
2) Confidence 0.15 Published 2002 Journal Respir Res Section Body Doc Link PMC64809 Disease Relevance 0.50 Pain Relevance 0.42

General Comments

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