INT17110

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Context Info
Confidence 0.65
First Reported 1991
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 60
Total Number 61
Disease Relevance 19.57
Pain Relevance 4.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (PSMD1) cytosol (PSMD1) nucleoplasm (PSMD1)
small molecule metabolic process (PSMD1) cellular nitrogen compound metabolic process (PSMD1)
Anatomy Link Frequency
faces 11
lung 2
canal 1
facet 1
primary somatosensory cortex 1
PSMD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 114 100.00 Very High Very High Very High
chemokine 63 100.00 Very High Very High Very High
primary somatosensory cortex 57 100.00 Very High Very High Very High
Inflammation 51 100.00 Very High Very High Very High
imagery 72 98.32 Very High Very High Very High
Pain 206 97.52 Very High Very High Very High
metalloproteinase 59 96.12 Very High Very High Very High
peptic ulcer disease 22 95.24 Very High Very High Very High
addiction 83 95.04 Very High Very High Very High
rheumatoid arthritis 1 94.84 High High
Disease Link Frequency Relevance Heat
Critical Illness 74 100.00 Very High Very High Very High
INFLAMMATION 69 100.00 Very High Very High Very High
Low Back Pain 20 100.00 Very High Very High Very High
Anxiety Disorder 342 99.92 Very High Very High Very High
Sprains And Strains 218 99.86 Very High Very High Very High
Colon Cancer 53 99.44 Very High Very High Very High
Cockayne Syndrome 165 99.42 Very High Very High Very High
Ulcers 45 99.12 Very High Very High Very High
Metastasis 38 99.12 Very High Very High Very High
Systolic Murmurs 3 98.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Examination revealed tenderness on palpation of the L-5 and S-1 spinous processes, straightening of the lumbar spine, and exquisite pain on 10 degrees of hyperextension.
Gene_expression (palpation) of S-1 in spine associated with pain
1) Confidence 0.65 Published 1991 Journal Orthop Rev Section Abstract Doc Link 1876459 Disease Relevance 0.19 Pain Relevance 0.24
Radiographs of the lumbar spine revealed bilateral pedicle defects at L-3, L-4, and L-5, with widening of the spinal canal and spondylolisthesis of L-5 on S-1.
Gene_expression (spondylolisthesis) of S-1 in canal associated with low back pain
2) Confidence 0.65 Published 1995 Journal AJNR Am J Neuroradiol Section Abstract Doc Link 7502963 Disease Relevance 0.29 Pain Relevance 0.14
Early monkey studies by Murthy and Fetz (1992) showed that oscillations are also present in primary somatosensory cortex (S1), and that there is beta-band coherence between M1 and S1.
Gene_expression (present) of S1 in primary somatosensory cortex associated with primary somatosensory cortex
3) Confidence 0.48 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2927302 Disease Relevance 0.34 Pain Relevance 0.34
In addition, the types of hepatectomy have changed since the introduction of portal vein embolization; the performance of central hepatectomies, including S1 resection, S1 + 4 resection, S1 + 5 + 8 resection, and S1 + 4 + 5 + 8 resection, has become uncommon, while typical major hepatectomies including right or left hepatectomy, and right or left trisectionectomy have been increasingly performed18–20 (level IV).
Gene_expression (resection) of S1 in portal vein
4) Confidence 0.46 Published 2008 Journal J Hepatobiliary Pancreat Surg Section Body Doc Link PMC2794354 Disease Relevance 0.28 Pain Relevance 0.03
We designed the behavioral paradigm to reduce or eliminate potential confounding explanations for these effects, such as capture by apparent motion and repulsive aftereffects, where static S1 facial expressions bias expression perception of S2 faces away from the S1 expression (Webster et al. 2004).
Gene_expression (expression) of S1 in faces
5) Confidence 0.45 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.25 Pain Relevance 0
It allows clear detection of S1, S2 and S3 sounds, S2 split, systolic murmur, and intensity of these components.
Spec (clear) Gene_expression (detection) of S1 associated with systolic murmurs
6) Confidence 0.42 Published 2007 Journal Biomed Eng Online Section Abstract Doc Link PMC1899182 Disease Relevance 0.20 Pain Relevance 0
We designed the behavioral paradigm to reduce or eliminate potential confounding explanations for these effects, such as capture by apparent motion and repulsive aftereffects, where static S1 facial expressions bias expression perception of S2 faces away from the S1 expression (Webster et al. 2004).
Gene_expression (expressions) of S1 in faces
7) Confidence 0.39 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.26 Pain Relevance 0
We matched the expressions of the static S1 faces to the 3 possible endpoints of the predictable and scrambled sequences: (28%, 45%, or 63% fearfulness).
Gene_expression (expressions) of S1 in faces associated with anxiety disorder
8) Confidence 0.39 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.45 Pain Relevance 0.08
Following presentation of S1 (Fig. 1c) and an 800-ms interstimulus interval, participants then viewed a brief (250 ms) static target face (S2).
Gene_expression (presentation) of S1 in face
9) Confidence 0.39 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.46 Pain Relevance 0.08
For simplicity, this activation is referred to in the manuscript as S1 activation.
Gene_expression (activation) of S1
10) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2778627 Disease Relevance 0 Pain Relevance 0.04
We found matching results for the static S1 faces: fearfulness of static S1 faces (28%, 45%, or 63%) strongly enhanced fear perception of S2 faces, reflected by a significant main effect of static S1 fearfulness, F2,40 = 13.93, MSE = 0.09, P < 0.0001.


Gene_expression (faces) of S1 in faces associated with anxiety disorder
11) Confidence 0.34 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.89 Pain Relevance 0.07
As aftereffects seem to depend also on the size of the expression difference between the S1 and S2 stimuli, we chose S1 stimuli that were close to S2 face expression (Fig. 1a).
Gene_expression (expression) of S1 in face
12) Confidence 0.34 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.21 Pain Relevance 0
We designed the behavioral paradigm to reduce or eliminate potential confounding explanations for these effects, such as capture by apparent motion and repulsive aftereffects, where static S1 facial expressions bias expression perception of S2 faces away from the S1 expression (Webster et al. 2004).
Gene_expression (expressions) of S1 in faces
13) Confidence 0.34 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.26 Pain Relevance 0
As before, the predictable sequences heightened responses compared with the static S1 faces, as well as to the scrambled sequences.
Gene_expression (faces) of S1 in faces
14) Confidence 0.34 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0 Pain Relevance 0
Participants viewed static S1 faces for the same duration as predictable and scrambled S1 sequences (360 ms).
Gene_expression (predictable) of S1 in faces
15) Confidence 0.34 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.44 Pain Relevance 0.09
Participants viewed static S1 faces for the same duration as predictable and scrambled S1 sequences (360 ms).
Gene_expression (faces) of S1 in faces
16) Confidence 0.34 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.43 Pain Relevance 0.09
S1 connections
Gene_expression (connections) of S1
17) Confidence 0.34 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2577683 Disease Relevance 0 Pain Relevance 0.12
S-1 (TS-1®, Taiho Pharmaceutical Co., Ltd.) is an orally active combination of tegafur (a 5-FU prodrug), gimeracil (an inhibitor of dihydropyrimidine dehydrogenase), and oteracil (which inhibits the phosphorylation of 5-FU in the gastrointestinal tract, thereby reducing the gastrointestinal toxic effects of 5-FU) and is widely used in Asia for the management of gastric cancer.
Gene_expression (used) of S-1 associated with stomach cancer
18) Confidence 0.33 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2856525 Disease Relevance 0.70 Pain Relevance 0
Participants’ fear perception of subsequent (S2) static target faces was biased toward the expression causing the preceding predictable sequence (S1), underscoring a role for the representation of dynamics in the perception of facial expressions.
Gene_expression (expression) of S1 in faces associated with anxiety disorder
19) Confidence 0.30 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.10 Pain Relevance 0.03
U1(s1,s2*)foralls1?
Gene_expression (foralls1) of s1
20) Confidence 0.28 Published 2008 Journal Philosophical Transactions of the Royal Society B: Biological Sciences Section Body Doc Link PMC2581786 Disease Relevance 0.26 Pain Relevance 0

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