INT171118

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Context Info
Confidence 0.26
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.59
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Spg7) mitochondrion (Spg7) cell adhesion (Spg7)
mitochondrion organization (Spg7)
Anatomy Link Frequency
monocytes 1
Spg7 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 14 96.72 Very High Very High Very High
Arthritis 100 95.92 Very High Very High Very High
rheumatoid arthritis 6 86.20 High High
Inflammation 22 80.48 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 98.68 Very High Very High Very High
Cancer 4 98.44 Very High Very High Very High
Necrosis 4 98.16 Very High Very High Very High
INFLAMMATION 30 96.72 Very High Very High Very High
Arthritis 92 95.92 Very High Very High Very High
Infectious Arthritis 20 93.84 High High
Severe Combined Immunodeficiency 18 89.60 High High
Rheumatoid Arthritis 6 86.20 High High
Seronegative Spondarthritis 2 85.20 High High
Crystal Associated Disease 2 62.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several studies have shown that staphylococcal PGN stimulates human monocytes to release tumour necrosis factor-alpha (TNF-?)
Localization (staphylococcal) of PGN in monocytes associated with necrosis and cancer
1) Confidence 0.26 Published 2001 Journal Arthritis Res Section Body Doc Link PMC64849 Disease Relevance 1.33 Pain Relevance 0.45
Eradication of bacteria using antibiotics might not be sufficient to eliminate disease symptoms, since the proinflammatory bacterial products including PGN released from resident bacteria in concert with bacterial DNA, might promote a continuous inflammatory response.
Localization (released) of PGN associated with inflammatory response and disease
2) Confidence 0.24 Published 2001 Journal Arthritis Res Section Body Doc Link PMC64849 Disease Relevance 1.26 Pain Relevance 0.51

General Comments

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