INT171145

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Context Info
Confidence 0.59
First Reported 2002
Last Reported 2011
Negated 9
Speculated 2
Reported most in Body
Documents 274
Total Number 276
Disease Relevance 93.55
Pain Relevance 69.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Fig4) Golgi apparatus (Fig4) endoplasmic reticulum (Fig4)
Anatomy Link Frequency
neurons 15
blood 5
plasma 4
nerve 4
spike 3
Fig4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1468 100.00 Very High Very High Very High
Pain 1063 100.00 Very High Very High Very High
dorsal root ganglion 1042 100.00 Very High Very High Very High
Spinal cord 934 100.00 Very High Very High Very High
Glutamate 675 100.00 Very High Very High Very High
qutenza 673 100.00 Very High Very High Very High
cytokine 503 100.00 Very High Very High Very High
Dopamine 501 100.00 Very High Very High Very High
long-term potentiation 488 100.00 Very High Very High Very High
allodynia 397 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 1725 100.00 Very High Very High Very High
Ganglion Cysts 1365 100.00 Very High Very High Very High
Pain 1296 100.00 Very High Very High Very High
Stress 1254 100.00 Very High Very High Very High
Injury 1124 100.00 Very High Very High Very High
Neuropathic Pain 931 100.00 Very High Very High Very High
Apoptosis 810 100.00 Very High Very High Very High
Nociception 630 100.00 Very High Very High Very High
Diabetes Mellitus 608 100.00 Very High Very High Very High
Aggression 401 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In sessions 2–5 in which the rats received noncontingent amphetamine, the visual signal group markedly increased lever pressing (Fig. 2A; a significant main concentration effect, F2,6?
Positive_regulation (increased) of Fig in lever
1) Confidence 0.59 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806927 Disease Relevance 0 Pain Relevance 0
However, the careful choice of the size of the cylinder and the position of the fiber allowed us to identify a more favorable situation, as is illustrated in Fig. 8
Positive_regulation (illustrated) of Fig
2) Confidence 0.43 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3000694 Disease Relevance 0 Pain Relevance 0
Micturition pressure was less affected and generally increased (Fig. 9).
Positive_regulation (increased) of Fig associated with overactive bladder
3) Confidence 0.43 Published 2005 Journal BMC Pharmacol Section Body Doc Link PMC1274333 Disease Relevance 0.53 Pain Relevance 0.21
While cocaine MI was as effective as cocaine HCl in causing the glutamate release responsible for the initial phase of the dopamine increase (Fig. 1B vs 1E), it was less effective than cocaine HCl at reinstating the cocaine-seeking lever-press habit (Fig. 1A vs 1D) and at causing dendritic dopamine release (Fig. 1C vs 1F).
Positive_regulation (increase) of Fig in lever associated with dopamine, glutamate and cocaine
4) Confidence 0.42 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2475658 Disease Relevance 0 Pain Relevance 1.36
0.10 for three out of four paws) was also seen in an increase in stand index (the speed at which the paws lose contact with the glass plate) (Fig. 4C) and a decrease in swing (the duration of no contact with the glass plate in a step cycle) (Fig. 4D).
Positive_regulation (increase) of Fig
5) Confidence 0.41 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2924851 Disease Relevance 0.19 Pain Relevance 0
However, the fact that no differences in LH secretion were observed in response to SD (Fig. 7) suggests that this is not the case in F344 rats.
Positive_regulation (response) of Fig
6) Confidence 0.40 Published 2002 Journal BMC Physiol Section Body Doc Link PMC122066 Disease Relevance 0.13 Pain Relevance 0
Additionally, GFAP labeled cells were more abundant in both the periventricular white matter (Fig. 7H,I) and the area surrounding the cerebral aqueduct (Fig. 8H,I).


Positive_regulation (abundant) of Fig in white matter
7) Confidence 0.39 Published 2007 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1899521 Disease Relevance 0.16 Pain Relevance 0
In the parietal cortex, GFAP levels in 5d hydrocephalic animals as measured by scanning densitometry of Western blots, were significantly increased by 3.68X compared to control animals (p < 0.01) (Fig. 4).
Positive_regulation (increased) of Fig in parietal cortex
8) Confidence 0.39 Published 2007 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1899521 Disease Relevance 0.23 Pain Relevance 0
Surprisingly, despite its disorganization, the global SMI in adult PA rats was significantly increased (Fig. 4D; U test p<0.05).
Positive_regulation (increased) of Fig associated with asphyxia
9) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009724 Disease Relevance 0.24 Pain Relevance 0
Like quadrant crossings, GLU increased dramatically when lights were off regardless of treatment (Fig. 2A,B).
Positive_regulation (increased) of Fig associated with glutamate
10) Confidence 0.39 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1884166 Disease Relevance 0 Pain Relevance 0.14
In the connection shown in Fig. 16B1 and B2, the EPSC components corresponding to activation of both the proximal synapse 1 and the distal synapse 2 were potentiated (Fig. 16B, right).
Positive_regulation (potentiated) of Fig in synapse
11) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2778873 Disease Relevance 0 Pain Relevance 0
In 15 pairs, the protocol induced depression (Fig. 12, LTD, 1 Hz) recorded for 14–50 min.
Positive_regulation (induced) of Fig associated with depression
12) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2778873 Disease Relevance 0.22 Pain Relevance 0.11
One of these connections first showed EPSCs with only one component corresponding to activation of more distal synapse 2 (Fig. 16A1).
Positive_regulation (activation) of Fig in synapse
13) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2778873 Disease Relevance 0 Pain Relevance 0
Instead, FS-stress induced rapid and significant changes in the amount of SNARE complexes, in line with the rapid increase of glutamate release (Fig. 4).
Positive_regulation (increase) of Fig associated with stress and glutamate
14) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797327 Disease Relevance 0.47 Pain Relevance 0.34
GSH activity increased (P < 0.001) in diabetic rats (Fig. 10).
Positive_regulation (increased) of Fig associated with diabetes mellitus
15) Confidence 0.35 Published 2008 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2529380 Disease Relevance 1.05 Pain Relevance 0
For E-treated rats, only the area of endosteal callus formation showed a significant increase (Fig. 4b), which proves higher bone formation at all times of the monitored healing process.
Positive_regulation (increase) of Fig
16) Confidence 0.35 Published 2008 Journal Langenbecks Arch Surg Section Body Doc Link PMC2814041 Disease Relevance 0.15 Pain Relevance 0
The content of Evan's blue increased as early as 6h, and remained unchanged until 6h, but robustly increased at 48 h after stroke in the ischemic penumbra (Fig. 8), suggesting a time-dependent BBB leakage.
Positive_regulation (increased) of Fig associated with stroke
17) Confidence 0.34 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588536 Disease Relevance 0.82 Pain Relevance 0.04
Basal lactate levels were significantly elevated in CPIP rats, particularly early after reperfusion (P = 0.00036) (Fig. 6a).
Positive_regulation (elevated) of Fig associated with pain
18) Confidence 0.34 Published 2008 Journal Mol Pain Section Body Doc Link PMC2584041 Disease Relevance 1.56 Pain Relevance 1.56
= 0.04); thus, nicotine pretreatment during adolescence promoted the induction of cocaine locomotor sensitization (Fig. 3b).
Positive_regulation (induction) of Fig associated with nicotine and cocaine
19) Confidence 0.34 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2764852 Disease Relevance 0 Pain Relevance 0.81
-E2 on KCl-induced contraction (Fig. 3F).


Positive_regulation (induced) of Fig
20) Confidence 0.33 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1201169 Disease Relevance 0 Pain Relevance 0.13

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