INT171223

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 3.81
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Ncam1) cell adhesion (Ncam1) plasma membrane (Ncam1)
Anatomy Link Frequency
neural 2
muscle 1
stage 19 1
NK cells 1
Ncam1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 14 84.68 Quite High
Inflammation 27 78.56 Quite High
agonist 42 67.52 Quite High
rheumatoid arthritis 45 67.36 Quite High
cINOD 1 65.40 Quite High
withdrawal 2 26.64 Quite Low
metalloproteinase 2 9.44 Low Low
Inflammatory response 6 7.48 Low Low
Action potential 22 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 34 100.00 Very High Very High Very High
Teratocarcinoma 2 98.64 Very High Very High Very High
Hemophagocytic Lymphohistiocytosis 22 87.80 High High
Macrophage Activation Syndrome 29 87.52 High High
Cv Unclassified Under Development 12 84.68 Quite High
Injury 2 83.44 Quite High
Aging 4 79.80 Quite High
INFLAMMATION 34 78.56 Quite High
Disease 13 77.60 Quite High
Rheumatoid Arthritis 45 67.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since muscle inactivity leads to up-regulation of NCAM (Cashman et al. 1987), it is likely to occur after exposure to BoNT/A and may therefore play an important part in stimulating both local and remote sprouting.
Regulation (regulation) of NCAM in muscle
1) Confidence 0.20 Published 2008 Journal The Journal of Physiology Section Body Doc Link PMC2538785 Disease Relevance 0.17 Pain Relevance 0
positively correlated with modulation of neural cell adhesion molecule (NCAM)
Regulation (modulation) of neural cell adhesion molecule in neural associated with adhesions
2) Confidence 0.16 Published 2008 Journal PPAR Research Section Body Doc Link PMC2581793 Disease Relevance 1.41 Pain Relevance 0.15
positively correlated with modulation of neural cell adhesion molecule (NCAM)
Regulation (modulation) of NCAM in neural associated with adhesions
3) Confidence 0.16 Published 2008 Journal PPAR Research Section Body Doc Link PMC2581793 Disease Relevance 1.42 Pain Relevance 0.15
This is known to be true in two of the examples cited above (mdx mice, NCAM up-regulation).
Regulation (regulation) of NCAM
4) Confidence 0.12 Published 2008 Journal The Journal of Physiology Section Body Doc Link PMC2538785 Disease Relevance 0.11 Pain Relevance 0
In contrast, CD56bright NK cells might have a function in regulating the CD56dim perforinbright cells, and in this case their disappearance might have an effect on cytolytic activity in some sJRA patients.
Regulation (regulating) of CD56dim in NK cells
5) Confidence 0.09 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1064882 Disease Relevance 0.70 Pain Relevance 0.14
In PN-1 treated embryos, NCAM immunoreactivity was instead present at stage 19.
Regulation (immunoreactivity) of NCAM in stage 19
6) Confidence 0.07 Published 2002 Journal BMC Dev Biol Section Body Doc Link PMC65692 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox