INT171273

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF12, IL8) extracellular space (TNFSF12, IL8) extracellular region (TNFSF12, IL8)
cell differentiation (TNFSF12) intracellular (IL8) plasma membrane (TNFSF12)
TNFSF12 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 11 80.72 Quite High
Inflammation 19 26.56 Quite Low
cytokine 11 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 26.56 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In synoviocytes, basal levels of IL-8, MMP-1 and PGE2 are decreased by the blocking anti-TWEAK mAb
anti-TWEAK mAb Negative_regulation (decreased) of Gene_expression (levels) of IL-8
1) Confidence 0.01 Published 2002 Journal Arthritis Res Section Body Doc Link PMC83846 Disease Relevance 0 Pain Relevance 0.04

General Comments

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