INT171277

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF12, IL8) extracellular space (TNFSF12, IL8) extracellular region (TNFSF12, IL8)
cell differentiation (TNFSF12) intracellular (IL8) plasma membrane (TNFSF12)
Anatomy Link Frequency
fibroblasts 3
TNFSF12 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 11 100.00 Very High Very High Very High
Inflammatory response 3 77.92 Quite High
Inflammation 19 71.28 Quite High
Inflammatory mediators 1 46.36 Quite Low
cytokine 11 34.40 Quite Low
COX2 2 23.44 Low Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 77.92 Quite High
Disease 8 61.60 Quite High
Adhesions 2 24.60 Low Low
Death 6 20.68 Low Low
Cancer 4 10.60 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In dermal fibroblasts, BEB3-crosslinked hTWEAK was shown to increase the mRNA level of three chemokines of the CXC or CC families, IL-8, MCP-1 and RANTES.
hTWEAK Binding (crosslinked) of in fibroblasts Positive_regulation (increase) of Transcription (level) of IL-8 in fibroblasts associated with chemokine
1) Confidence 0.01 Published 2002 Journal Arthritis Res Section Body Doc Link PMC83846 Disease Relevance 0.21 Pain Relevance 0.12

General Comments

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