INT171283

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF12, IL8) extracellular space (TNFSF12, IL8) extracellular region (TNFSF12, IL8)
cell differentiation (TNFSF12) intracellular (IL8) plasma membrane (TNFSF12)
TNFSF12 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 79.00 Quite High
chemokine 11 34.72 Quite Low
Inflammation 19 25.56 Quite Low
metalloproteinase 6 15.88 Low Low
cytokine 11 10.96 Low Low
Inflammatory response 3 9.28 Low Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 78.60 Quite High
Adhesions 2 57.24 Quite High
Death 6 53.32 Quite High
Cancer 4 43.24 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, blocking anti-TNF antibodies were inactive in the secretion of IL-8, MMP-1, PGE2, RANTES and IP-10 induced by TWEAK, ruling out any involvement of TNF in TWEAK activity.
TWEAK Positive_regulation (induced) of Localization (secretion) of IL-8
1) Confidence 0.01 Published 2002 Journal Arthritis Res Section Body Doc Link PMC83846 Disease Relevance 0.19 Pain Relevance 0.04

General Comments

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