INT171323

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Context Info
Confidence 0.57
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 4.13
Pain Relevance 1.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) cell-cell signaling (IL1B)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 89 99.36 Very High Very High Very High
cytokine 78 98.08 Very High Very High Very High
rheumatoid arthritis 70 93.52 High High
antagonist 17 86.84 High High
Inflammatory mediators 1 85.28 High High
methotrexate 26 85.12 High High
Arthritis 22 78.92 Quite High
addiction 5 71.56 Quite High
agonist 22 62.56 Quite High
alcohol 1 61.92 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 100 99.36 Very High Very High Very High
Cancer 32 96.64 Very High Very High Very High
Rheumatoid Arthritis 70 93.52 High High
Breast Cancer 1 92.96 High High
Injury 1 87.32 High High
Adhesions 2 87.00 High High
Death 10 83.08 Quite High
Mucositis 38 81.84 Quite High
Dysphagia 4 80.48 Quite High
Disease 54 80.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the number of IL-1?
Phosphorylation (number) of IL-1
1) Confidence 0.57 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206382 Disease Relevance 0 Pain Relevance 0.14
A correlation between IL-1 and TNF-?
Phosphorylation (correlation) of IL-1
2) Confidence 0.47 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2837669 Disease Relevance 1.72 Pain Relevance 0.62
AMG 108 (Amgen Inc., Thousand Oaks, CA, USA) is a fully human IgG2 monoclonal antibody that binds IL-1R type 1 and nonselectively inhibits the activity of both forms of IL-1 (IL-1?
Phosphorylation (forms) of IL-1
3) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991028 Disease Relevance 0.83 Pain Relevance 0.50
AMG 108 (Amgen Inc., Thousand Oaks, CA, USA) is a fully human IgG2 monoclonal antibody that binds IL-1R type 1 and nonselectively inhibits the activity of both forms of IL-1 (IL-1?
Phosphorylation (forms) of IL-1
4) Confidence 0.39 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991028 Disease Relevance 0.83 Pain Relevance 0.50
Although hTWEAK has proinflammatory properties, these are much less pronounced than those of IL-1?
Phosphorylation (those) of IL-1
5) Confidence 0.18 Published 2002 Journal Arthritis Res Section Body Doc Link PMC83846 Disease Relevance 0.66 Pain Relevance 0.07
These data suggest the existence of a release mechanism of IL-1?
Phosphorylation (mechanism) of IL-1
6) Confidence 0.15 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 0.09 Pain Relevance 0.11

General Comments

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