INT171389

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Context Info
Confidence 0.16
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Src, Mapk1) cytoplasm (Src, Mapk1) nucleus (Src, Mapk1)
cytoskeleton (Src, Mapk1) cell cycle (Src, Mapk1) kinase activity (Src, Mapk1)
Src (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 2 83.76 Quite High
agonist 8 79.60 Quite High
Opioid 23 50.00 Quite Low
antagonist 14 16.80 Low Low
opioid receptor 12 5.00 Very Low Very Low Very Low
MU agonist 4 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
orphanin 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 13 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the Src inhibitor, PP1 or the expression of a dominant-negative Src mutant, will reduce GPCR-mediated transphosphorylation of the EGFR and GPCR-mediated ERK activation to varying degrees (partial to total), suggesting that at least two different tyrosine kinases can be involved [18].
Src Positive_regulation (mediated) of Positive_regulation (activation) of ERK
1) Confidence 0.16 Published 2002 Journal BMC Pharmacol Section Body Doc Link PMC88976 Disease Relevance 0 Pain Relevance 0.11

General Comments

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