INT171402

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Context Info
Confidence 0.36
First Reported 2001
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.81
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ppap2a) plasma membrane (Ppap2a)
Anatomy Link Frequency
heart 2
Ppap2a (Mus musculus)
Pain Link Frequency Relevance Heat
cva 3 76.32 Quite High
Inflammatory mediators 5 50.00 Quite Low
cytokine 7 49.04 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 27 96.44 Very High Very High Very High
Increased Venous Pressure Under Development 22 88.72 High High
Secondary Pulmonary Hypertension 39 85.44 High High
Pulmonary Disease 36 84.36 Quite High
Pulmonary Embolism 3 76.32 Quite High
INFLAMMATION 11 50.00 Quite Low
Hypoxia 3 17.84 Low Low
Adult Respiratory Distress Syndrome 12 5.00 Very Low Very Low Very Low
Lung Injury 10 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reduction in PVRI was not proportional to the increase in the cardiac index, leading to an increase in MPAP.
Neg (not) Positive_regulation (leading) of Positive_regulation (increase) of MPAP
1) Confidence 0.36 Published 2001 Journal Crit Care Section Body Doc Link PMC96124 Disease Relevance 0.31 Pain Relevance 0.04
Administration of INO caused a reduction in mean pulmonary arterial pressure (MPAP), an increase in PaO2 with a significant reduction in venous admixture effect (Qs/Qt).Dobutamine administration caused an increase in cardiac index and MPAP, with a decrease in PaO2 as a result of a higher Qs/Qt.
Positive_regulation (caused) of Positive_regulation (increase) of MPAP
2) Confidence 0.36 Published 2001 Journal Crit Care Section Abstract Doc Link PMC96124 Disease Relevance 0.32 Pain Relevance 0
Dobutamine infusion caused an increase in cardiac index, heart rate, systemic vascular index (SVI), and MPAP with no change in CVP, PAOP, and MAP.
Positive_regulation (caused) of Positive_regulation (increase) of MPAP in heart
3) Confidence 0.36 Published 2001 Journal Crit Care Section Body Doc Link PMC96124 Disease Relevance 0.18 Pain Relevance 0
Endotoxin exposure caused an increase in the MPAP and the pulmonary vascular resistance, whereas the cardiac output remained unaltered.
Positive_regulation (caused) of Positive_regulation (increase) of MPAP
4) Confidence 0.07 Published 2008 Journal Crit Care Section Body Doc Link PMC2592770 Disease Relevance 0 Pain Relevance 0

General Comments

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