INT171423

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Context Info
Confidence 0.10
First Reported 2002
Last Reported 2007
Negated 1
Speculated 2
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.80
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (DNLZ)
Anatomy Link Frequency
HeLa 1
fibroblast 1
DNLZ (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 67.40 Quite High
Pain 5 63.16 Quite High
depression 16 5.00 Very Low Very Low Very Low
tolerance 10 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
beta blocker 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 32 97.28 Very High Very High Very High
Apoptosis 47 94.02 High High
Carcinoma 4 86.96 High High
Hepatocellular Cancer 5 86.24 High High
Porphyria 8 85.08 High High
Metastasis 1 77.64 Quite High
Infection 11 71.16 Quite High
Abdominal Pain 1 67.40 Quite High
Fever 2 66.24 Quite High
Vomiting 1 65.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
But, unlike cancer cells, normal cells have intact programmed cell death mechanisms and most treatments designed to kill cancer cells also reach normal cell, resulting in side effects to organs including the gastrointestinal tract, bone marrow etc., The aim of the present study was to purify the active peptide in the fish venom and to investigate its antiproliferative effect on cultured HEp2, HeLa and normal lymphocytes In vitro and thereby its possible mechanism of action.


Spec (investigate) Regulation (effect) of HEp2 in HeLa associated with cancer and apoptosis
1) Confidence 0.10 Published 2006 Journal J Carcinog Section Body Doc Link PMC1705806 Disease Relevance 1.10 Pain Relevance 0.06
In these ways, the HEP intervention will plausibly control for Hawthorne effect but exclusively through interventions that have been shown to have little or no impact on gait speed.
Regulation (control) of HEP
2) Confidence 0.08 Published 2007 Journal BMC Neurol Section Body Doc Link PMC2222229 Disease Relevance 0.06 Pain Relevance 0.06
Of the 48 NPAs studied, we observed no cytopathic effect on HEp-2, MDCK, human embryonic lung fibroblast, and BGM monolayers.
Neg (no) Regulation (effect) of HEp-2 in fibroblast
3) Confidence 0.05 Published 2003 Journal Emerging Infectious Diseases Section Body Doc Link PMC3016779 Disease Relevance 0.12 Pain Relevance 0
In this study, we have examined the effect of ALA on human hepatocarcinoma HEP G2 and HEP 3B cell lines viability.
Spec (examined) Regulation (effect) of HEP G2
4) Confidence 0.04 Published 2002 Journal BMC Cancer Section Body Doc Link PMC101407 Disease Relevance 0.53 Pain Relevance 0.07

General Comments

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