INT171476

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Context Info
Confidence 0.42
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HTR1A) signal transducer activity (HTR1A)
Anatomy Link Frequency
neurons 2
HTR1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Rostral ventrolateral medulla 2 98.08 Very High Very High Very High
Fibrositis 51 97.82 Very High Very High Very High
Pain 63 89.20 High High
Neuropeptide 1 74.40 Quite High
depression 8 63.76 Quite High
rheumatoid arthritis 1 17.68 Low Low
Pain score 8 5.00 Very Low Very Low Very Low
biopsychosocial 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Pain scale 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 51 97.82 Very High Very High Very High
Pain 73 89.20 High High
Chronic Disease 1 85.52 High High
Cognitive Disorder 1 73.12 Quite High
Depression 8 63.76 Quite High
Neurosis 9 56.52 Quite High
Anxiety Disorder 8 55.40 Quite High
Stress 7 49.92 Quite Low
Post-traumatic Stress Disorder 1 35.84 Quite Low
Chronic Fatigue Syndrome 1 23.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One possible explanation for this finding is that fibromyalgia patients display perturbations in central sympathetic system with reduced reactivity, which might be due to reduced sensitivity of 5-HT1A receptors on sympathoexcitatory neurons in the rostral ventrolateral medulla.
Negative_regulation (reduced) of Regulation (sensitivity) of 5-HT1A in neurons associated with rostral ventrolateral medulla and fibrositis
1) Confidence 0.42 Published 2002 Journal BMC Musculoskelet Disord Section Body Doc Link PMC113754 Disease Relevance 1.05 Pain Relevance 0.52

General Comments

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