INT171511

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.53
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 4.17
Pain Relevance 2.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (EP300) transferase activity, transferring acyl groups (EP300) DNA binding (EP300)
cytoplasm (EP300) nucleolus (EP300) nucleus (EP300)
Anatomy Link Frequency
parietal 2
Hip 1
EP300 (Homo sapiens)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 74 99.54 Very High Very High Very High
Nicotine 59 98.36 Very High Very High Very High
drug abuse 69 96.56 Very High Very High Very High
addiction 237 94.32 High High
opiate 66 86.80 High High
methadone 59 86.04 High High
depression 40 85.72 High High
Opioid 44 85.04 High High
cocaine 275 79.88 Quite High
withdrawal 84 72.36 Quite High
Disease Link Frequency Relevance Heat
Encephalopathy 12 99.20 Very High Very High Very High
Respiratory Failure 30 99.00 Very High Very High Very High
Mental Disorders 36 98.40 Very High Very High Very High
Drug Dependence 418 96.56 Very High Very High Very High
Cognitive Disorder 163 95.84 Very High Very High Very High
Conduct Disorder 15 95.56 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 95 93.44 High High
Apoptosis 74 92.04 High High
Affective Disorder 13 90.96 High High
Cancer 326 86.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The fact that we found no electrode × group interactions indicates that the effects of nicotine may be a more general one and not be related specifically to frontal or parietal sources of the P300.
Gene_expression (sources) of P300 in parietal associated with nicotine
1) Confidence 0.53 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC2198909 Disease Relevance 0.07 Pain Relevance 1.00
Supporting this notion, Polich et al. (1994) [68] compared the P300 elicited with auditory stimuli using a typical oddball paradigm with that elicited from a single stimulus procedure and concluded that the single-stimulus task produces the P300 in the same fashion as those elicited with the oddball paradigm.
Gene_expression (produces) of P300
2) Confidence 0.40 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2607283 Disease Relevance 0.05 Pain Relevance 0.07
Possible involvement of the ACC and Hip activities in generating the P300
Gene_expression (generating) of P300 in Hip associated with anterior cingulate cortex
3) Confidence 0.31 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2607283 Disease Relevance 0.07 Pain Relevance 0.19
We then assayed similarly expression levels for nuclear coactivators AIB1 [16], CBP [17], p300 [18], p/CIP [19], RAC3 [20], RIP140 [21], SRC1 [22], TIF1 [23], TIF2 [24] and TRIP1 [25].
Gene_expression (expression) of p300
4) Confidence 0.23 Published 2002 Journal BMC Pharmacol Section Body Doc Link PMC113761 Disease Relevance 0 Pain Relevance 0
On another front, P300 derangement occurs in both types of RF, and Its latency correlated well with severity of hypoxemia in both types.
Gene_expression (derangement) of P300 associated with respiratory failure
5) Confidence 0.21 Published 2010 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2846153 Disease Relevance 1.17 Pain Relevance 0.10
CBP/p300 potentiates ?
Gene_expression (/) of p300
6) Confidence 0.12 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.12 Pain Relevance 0.07
Through inhibiting HDAC, CBP/P300 will no longer be able to function as a co-activator, and possibly even repress the ?
Gene_expression (/) of P300
7) Confidence 0.12 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.51 Pain Relevance 0
In mammalian cells, CBP/P300 can also act as a co-activator of ?
Gene_expression (/) of P300
8) Confidence 0.12 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.42 Pain Relevance 0
CBP/p300 potentiates ?
Gene_expression (potentiates) of p300
9) Confidence 0.12 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.12 Pain Relevance 0.07
It was reported that these infrequent distracters elicit a frontocentral P300, so called P3a, whereas the rare targets elicit a parietal P300, so called P3b (Katayama and Polich 1996, 1998).
Gene_expression (elicit) of P300 in parietal
10) Confidence 0.09 Published 2008 Journal Appl Psychophysiol Biofeedback Section Body Doc Link PMC2259255 Disease Relevance 0.19 Pain Relevance 0.09
The P300 is usually obtained in an oddball paradigm, wherein two stimuli are presented in a random order, one of them frequent (standard) and another one rare (target) (Polich 1990).
Gene_expression (obtained) of P300
11) Confidence 0.09 Published 2008 Journal Appl Psychophysiol Biofeedback Section Body Doc Link PMC2259255 Disease Relevance 0.24 Pain Relevance 0.20
The P300 reduction and abnormal qEEG patterns are seen in mental disorders that often are comorbid with substance abuse, such as conduct disorder (Bauer and Hesselbrock 1999, 2001), ADHD (Bauer 1997; O’Connor et al. 1994), and bipolar or major affective disorder (Friedman and Squires-Wheeler 1994).
Gene_expression (reduction) of P300 associated with mental disorders, conduct disorder, affective disorder, drug abuse and attention deficit hyperactivity disorder
12) Confidence 0.09 Published 2008 Journal Appl Psychophysiol Biofeedback Section Body Doc Link PMC2259255 Disease Relevance 1.15 Pain Relevance 0.50
Both p300 and CBP can mediate acetylation of Rch1 and importin-?
Gene_expression (Both) of p300
13) Confidence 0.08 Published 2002 Journal Genome Biol Section Body Doc Link PMC139359 Disease Relevance 0 Pain Relevance 0
only considered the standard tone measurements and not the deviant and the P300
Gene_expression (deviant) of P300
14) Confidence 0.04 Published 2007 Journal Computational Intelligence and Neuroscience Section Body Doc Link PMC2233897 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox