INT171516

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Context Info
Confidence 0.25
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOA2) small molecule metabolic process (NCOA2) Golgi apparatus (NCOA2)
nucleus (NCOA2) cytoplasm (NCOA2) signal transducer activity (NCOA2)
Anatomy Link Frequency
intermediary 2
NCOA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 43 50.00 Quite Low
Inflammation 50 14.96 Low Low
antagonist 6 7.68 Low Low
palliative 9 5.00 Very Low Very Low Very Low
ischemia 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 123 99.68 Very High Very High Very High
Obesity 12 93.84 High High
Cancer 92 87.44 High High
Reprotox - General 1 2 49.52 Quite Low
Weight Gain 8 42.56 Quite Low
Pressure And Volume Under Development 34 25.68 Quite Low
INFLAMMATION 47 14.96 Low Low
Age-related Macular Degeneration 124 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 94 5.00 Very Low Very Low Very Low
Diabetes Mellitus 58 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Harigopal et al studied the prognostic significance of AIB1, TIF2 and NCoR protein expression in 670 breast cancer specimens by breast tissue microarray, and demonstrated the relationship of coregulatory proteins to ER, PR and HER2/neu.61 High AIB1 expression was associated with poor patient outcome (P = 0.002), while no association was noted for TIF2 (P = 0.376) or NCoR (P = 0.12).
Gene_expression (expression) of TIF2 associated with breast cancer
1) Confidence 0.25 Published 2010 Journal Clinical Medicine Insights. Oncology Section Body Doc Link PMC2883240 Disease Relevance 0.26 Pain Relevance 0
We then assayed similarly expression levels for nuclear coactivators AIB1 [16], CBP [17], p300 [18], p/CIP [19], RAC3 [20], RIP140 [21], SRC1 [22], TIF1 [23], TIF2 [24] and TRIP1 [25].
Gene_expression (expression) of TIF2
2) Confidence 0.15 Published 2002 Journal BMC Pharmacol Section Body Doc Link PMC113761 Disease Relevance 0 Pain Relevance 0
The transcription intermediary factor 2

(TIF-2), an adipogenic coactivator implicated in PPAR?

Gene_expression (The) of TIF-2 in intermediary
3) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2396446 Disease Relevance 0.19 Pain Relevance 0
The transcription intermediary factor 2

(TIF-2), an adipogenic coactivator implicated in PPAR?

Gene_expression (The) of transcription intermediary factor 2 in intermediary
4) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2396446 Disease Relevance 0.19 Pain Relevance 0

General Comments

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