INT171563

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Context Info
Confidence 0.30
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.93
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLAMF1)
Anatomy Link Frequency
Th1 cells 1
SLAMF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 78 66.36 Quite High
chemokine 30 63.60 Quite High
cytokine 30 62.28 Quite High
ketamine 30 5.00 Very Low Very Low Very Low
Inflammatory response 24 5.00 Very Low Very Low Very Low
anesthesia 18 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pneumonia 36 66.36 Quite High
Hypersensitivity 102 65.44 Quite High
Adhesions 18 54.36 Quite High
Asthma 150 5.80 Low Low
INFLAMMATION 66 5.40 Low Low
Disease 42 5.00 Very Low Very Low Very Low
Overdose 18 5.00 Very Low Very Low Very Low
Breast Cancer 18 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 12 5.00 Very Low Very Low Very Low
Aging 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, levels of soluble SLAM in serum were found to be lower in patients with elevated IgE than in normal controls, and low production of SLAM was associated with a Th2 response in vivo [36].
Gene_expression (production) of SLAM
1) Confidence 0.30 Published 2002 Journal Genome Biol Section Body Doc Link PMC115222 Disease Relevance 0 Pain Relevance 0.03
The downregulation of SLAM gene expression observed here after allergen challenge, which induces a Th2 response, is consistent with this earlier observation.
Gene_expression (expression) of SLAM gene
2) Confidence 0.30 Published 2002 Journal Genome Biol Section Body Doc Link PMC115222 Disease Relevance 0.17 Pain Relevance 0.08
One gene in particular is interesting - SLAM, signaling lymphocytic activation molecule.
Gene_expression (interesting) of SLAM
3) Confidence 0.26 Published 2002 Journal Genome Biol Section Body Doc Link PMC115222 Disease Relevance 0.25 Pain Relevance 0.09
In vitro studies in polarized human Th1 and Th2 CD4+ T-cell subsets indicate that higher levels of SLAM are observed in Th1 cells [35].
Gene_expression (levels) of SLAM in Th1 cells
4) Confidence 0.26 Published 2002 Journal Genome Biol Section Body Doc Link PMC115222 Disease Relevance 0.17 Pain Relevance 0.09
In addition, levels of soluble SLAM in serum were found to be lower in patients with elevated IgE than in normal controls, and low production of SLAM was associated with a Th2 response in vivo [36].
Gene_expression (levels) of SLAM
5) Confidence 0.23 Published 2002 Journal Genome Biol Section Body Doc Link PMC115222 Disease Relevance 0.10 Pain Relevance 0.05
One gene in particular is interesting - SLAM, signaling lymphocytic activation molecule.
Gene_expression (interesting) of signaling lymphocytic activation molecule
6) Confidence 0.23 Published 2002 Journal Genome Biol Section Body Doc Link PMC115222 Disease Relevance 0.25 Pain Relevance 0.09

General Comments

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