INT171688

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Context Info
Confidence 0.28
First Reported 2002
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.16
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Casp3) peptidase activity (Casp3) mitochondrion (Casp3)
nucleolus (Casp3) nucleus (Casp3) intracellular (Casp3)
Anatomy Link Frequency
neurons 2
Casp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 7 58.96 Quite High
Mechanotransduction 2 58.04 Quite High
Electroencephalography 13 41.16 Quite Low
Hippocampus 4 16.72 Low Low
gABA 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
GABAergic 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 85 94.68 High High
Fistula 42 90.88 High High
Convulsion 63 88.40 High High
Stress 33 51.48 Quite High
Epilepsy 19 50.00 Quite Low
Wound Healing 2 18.04 Low Low
Death 14 17.44 Low Low
Fetal Alcohol Syndrome 4 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Caspase-3 activities increased in prenatal rat hippocampal neurons
Positive_regulation (increased) of Transcription (activities) of Caspase-3 in neurons
1) Confidence 0.28 Published 2009 Journal Mol Brain Section Body Doc Link PMC2706809 Disease Relevance 0.27 Pain Relevance 0
There was an increase in caspase-3 and Bax mRNA levels at 4W.
Positive_regulation (increase) of Transcription (levels) of caspase-3
2) Confidence 0.09 Published 2002 Journal BMC Cardiovasc Disord Section Body Doc Link PMC119850 Disease Relevance 0.18 Pain Relevance 0.03
There was an increase in caspase-3 and Bax mRNA levels at 4 weeks.
Positive_regulation (increase) of Transcription (levels) of caspase-3
3) Confidence 0.09 Published 2002 Journal BMC Cardiovasc Disord Section Body Doc Link PMC119850 Disease Relevance 0.70 Pain Relevance 0.06

General Comments

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