INT171716

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2002
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.05
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Fap) extracellular space (Fap) plasma membrane (Fap)
Fap (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 33 82.16 Quite High
aspirin 72 50.00 Quite Low
Central nervous system 5 27.88 Quite Low
metalloproteinase 5 21.92 Low Low
Inflammation 9 16.40 Low Low
imagery 6 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 327 100.00 Very High Very High Very High
Syndrome 39 100.00 Very High Very High Very High
Familial Amyloidotic Polyneuropathy 21 100.00 Very High Very High Very High
Colon Cancer 106 99.84 Very High Very High Very High
Cancer 127 98.06 Very High Very High Very High
Disease 84 97.64 Very High Very High Very High
Adenomatous Polyps 15 92.48 High High
Polyps 98 84.16 Quite High
Stress 13 84.00 Quite High
Adenoma 89 78.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Identification of the mutated APC gene responsible for FAP enables presymptomatic and even prenatal diagnosis of the disease.
Regulation (responsible) of FAP associated with familial adenomatous polyposis and disease
1) Confidence 0.27 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 0.66 Pain Relevance 0
Recent data demonstrated clearly activation of the classical UPR pathways in FAP tissues not specialized in TTR synthesis but presenting extracellular TTR aggregate and fibril deposition [14].
Neg (not) Regulation (specialized) of FAP associated with familial amyloidotic polyneuropathy
2) Confidence 0.25 Published 2010 Journal J Transl Med Section Body Doc Link PMC2922089 Disease Relevance 0.46 Pain Relevance 0
Within 5 years of Herrera's discovery the gene responsible for FAP was identified simultaneously by two groups and is now commonly known as the Adenomatous Polyposis Coli (APC) gene [28-31].
Regulation (responsible) of FAP associated with familial adenomatous polyposis
3) Confidence 0.21 Published 2003 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2840009 Disease Relevance 0.91 Pain Relevance 0
Defects in the APC tumour suppressor gene are thought to play a role in greater than 70% of all colorectal cancers and is responsible for inherited syndromes of polyposis (FAP and Gardner's) [24,25].
Regulation (responsible) of FAP associated with syndrome, cancer, colon cancer and familial adenomatous polyposis
4) Confidence 0.19 Published 2002 Journal BMC Cancer Section Body Doc Link PMC122065 Disease Relevance 2.01 Pain Relevance 0.23

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox