INT171741

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Context Info
Confidence 0.44
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.38
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CXCR3) plasma membrane (CXCR3) cytoplasm (CXCR3)
signal transducer activity (CXCR3)
Anatomy Link Frequency
NK cells 1
keratinocytes 1
T cells 1
CXCR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 32 100.00 Very High Very High Very High
antagonist 2 91.64 High High
Inflammation 12 89.52 High High
cytokine 17 82.24 Quite High
Inflammatory marker 2 50.00 Quite Low
Inflammatory response 1 33.00 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Contact Dermatitis 28 99.64 Very High Very High Very High
Viral Infection 4 91.52 High High
Infection 136 90.64 High High
Dermatitis 4 89.52 High High
Viral Meningitis 4 89.20 High High
Severe Acute Respiratory Syndrome 2 87.12 High High
INFLAMMATION 14 78.72 Quite High
Hypersensitivity 11 71.44 Quite High
Hepatitis C Virus Infection 10 63.68 Quite High
Dengue 252 61.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results also confirmed the finding of Albanesi et al. who have shown that the majority of infiltrating cells in ACD are recruited by CXCR3 agonistic chemokines released by keratinocytes activated with IFN-gamma and TNF-alpha or IFN-gamma and IL-4 [45].
Localization (released) of CXCR3 in keratinocytes associated with chemokine and contact dermatitis
1) Confidence 0.44 Published 2002 Journal BMC Dermatol Section Body Doc Link PMC122084 Disease Relevance 0.72 Pain Relevance 0.28
IP-10 and I-TAC are both ligands for the CXCR3 chemokine receptor and the production of these chemokines leads to the recruitment of CXCR3 expressing T cells and NK cells [31],[32].
Localization (recruitment) of CXCR3 in NK cells associated with chemokine
2) Confidence 0.35 Published 2007 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2100376 Disease Relevance 0.83 Pain Relevance 0.25
IP-10 and I-TAC are both ligands for the CXCR3 chemokine receptor and the production of these chemokines leads to the recruitment of CXCR3 expressing T cells and NK cells [31],[32].
Localization (recruitment) of CXCR3 in T cells associated with chemokine
3) Confidence 0.12 Published 2007 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2100376 Disease Relevance 0.83 Pain Relevance 0.25

General Comments

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