INT171879

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Context Info
Confidence 0.03
First Reported 1999
Last Reported 2011
Negated 0
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 3.37
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ENOX1) extracellular space (ENOX1) oxidoreductase activity (ENOX1)
extracellular region (ENOX1) plasma membrane (ENOX1)
Anatomy Link Frequency
brain 1
ENOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 24 97.60 Very High Very High Very High
Inflammation 10 90.00 High High
neuralgia 1 85.28 High High
Pain threshold 36 84.32 Quite High
primary somatosensory cortex 282 76.96 Quite High
Pain 264 75.28 Quite High
Sciatica 3 70.24 Quite High
rheumatoid arthritis 29 63.96 Quite High
Chronic low back pain 5 50.00 Quite Low
cytokine 3 29.60 Quite Low
Disease Link Frequency Relevance Heat
Synovitis 50 100.00 Very High Very High Very High
Cancer 55 99.78 Very High Very High Very High
Syndrome 18 99.56 Very High Very High Very High
Seronegative Spondarthritis 10 97.60 Very High Very High Very High
Sacroiliitis 3 90.64 High High
INFLAMMATION 11 90.00 High High
Ankylosis 1 87.84 High High
Facial Neuralgia 1 85.84 High High
Pain 334 84.32 Quite High
Cognitive Disorder 26 75.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 1931, Ewing's broad contribution to the cancer field was recognized by Time magazine, which featured a sketch of his visage on the cover, calling him “Cancer Man Ewing” [3].
Time Binding (recognized) of associated with cancer
1) Confidence 0.03 Published 2011 Journal Sarcoma Section Body Doc Link PMC2995899 Disease Relevance 1.49 Pain Relevance 0.09
Time courses of low frequency (< 0.1 Hz) fluctuations where found to have a high degree of temporal correlation within sensorimotor regions and also with time courses in several other regions that can be associated with motor function, and they concluded that correlation of low frequency fluctuations in the resting state BOLD signal is a manifestation of functional connectivity of the brain.
time Binding (associated) of in brain
2) Confidence 0.01 Published 2010 Journal Nonlinear Biomed Phys Section Body Doc Link PMC2880806 Disease Relevance 0.08 Pain Relevance 0
Because we cannot reasonably make an assumption of constant or linear group differences over time, we will include an interaction between treatment group and time point.
time Binding (interaction) of
3) Confidence 0.01 Published 2010 Journal Trials Section Body Doc Link PMC2864260 Disease Relevance 0.21 Pain Relevance 0.15
In case of the LEP components we investigated if this effect was dependent on the defined areas by calculating the CONDITION × TIME × REGION interaction.
TIME Binding (interaction) of
4) Confidence 0.01 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC2248215 Disease Relevance 0.08 Pain Relevance 0.08
The CONDITION × TIME interaction was also not significant [F(3,33) = 0.080, P = 0.97].
TIME Binding (interaction) of
5) Confidence 0.01 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC2248215 Disease Relevance 0.15 Pain Relevance 0.15
The interaction of the CONDITION × TIME resulted in no significant interaction neither after the contraleteral [F(3,33) = 0.727, P = 0.543] or ipsilateral [F(3,33) = 1.694, P = 0.187] hand stimulation (Fig. 3).


TIME Binding (interaction) of
6) Confidence 0.01 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC2248215 Disease Relevance 0 Pain Relevance 0
We considered a psychophysical or an electrophysiological change only if the CONDITION × TIME interaction was significant.
TIME Binding (interaction) of
7) Confidence 0.01 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC2248215 Disease Relevance 0.07 Pain Relevance 0.07
The CONDITION × TIME interaction resulted in no significance [F(3,33) = 0.149, P = 0.93] (Fig. 5a).
TIME Binding (interaction) of
8) Confidence 0.01 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC2248215 Disease Relevance 0 Pain Relevance 0
The CONDITION × TIME interaction was also not significant [contralateral: F(3,33) = 2.669, P = 0.064; ipsilateral: F(3,33) = 0.418, P = 0.74].
TIME Binding (interaction) of
9) Confidence 0.01 Published 2007 Journal Exp Brain Res Section Body Doc Link PMC2248215 Disease Relevance 0 Pain Relevance 0.04
In this intriguing clinical syndrome, there is a clear association with specific pathogens...sometimes, a clear genetic predilection...sometimes, and complete resolution of the synovitis...most of the time.
most of the time Spec (clear) Binding (association) of associated with syndrome and synovitis
10) Confidence 0.01 Published 1999 Journal Arthritis Res Section Body Doc Link PMC128867 Disease Relevance 1.29 Pain Relevance 0.20

General Comments

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