INT171892

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Context Info
Confidence 0.05
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Adamts4) extracellular space (Adamts4) extracellular region (Adamts4)
proteinaceous extracellular matrix (Adamts4)
Adamts4 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 4 89.60 High High
cytokine 28 82.12 Quite High
rheumatoid arthritis 42 79.88 Quite High
Inflammation 18 11.20 Low Low
Arthritis 52 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
anti-cytokine treatment 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 42 79.88 Quite High
Severe Combined Immunodeficiency 2 77.32 Quite High
Arthritis 56 38.88 Quite Low
Osteoarthritis 1 31.68 Quite Low
INFLAMMATION 11 11.20 Low Low
Apoptosis 2 8.40 Low Low
Experimental Arthritis 8 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It also induces the release of active aggrecanase, which is the dominant enzyme responsible for proteoglycan loss.
Positive_regulation (induces) of Localization (release) of aggrecanase
1) Confidence 0.05 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128880 Disease Relevance 0.29 Pain Relevance 0.29

General Comments

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