INT171946

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Context Info
Confidence 0.47
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.86
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CCR5) plasma membrane (CCR5) cell-cell signaling (CCR5)
cytoplasm (CCR5) signal transducer activity (CCR5)
Anatomy Link Frequency
memory T cells 6
monocytes 2
CCR5 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 20 100.00 Very High Very High Very High
cytokine 8 65.60 Quite High
Inflammation 20 35.28 Quite Low
rheumatoid arthritis 32 30.96 Quite Low
antagonist 16 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Polymyalgia Rheumatica 152 95.96 Very High Very High Very High
Giant Cell Arteritis 156 89.36 High High
Sprains And Strains 4 77.92 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 77.04 Quite High
Recurrence 16 43.60 Quite Low
INFLAMMATION 20 35.28 Quite Low
Autoimmune Disease 4 33.20 Quite Low
Rheumatoid Arthritis 32 30.96 Quite Low
Disease 32 27.92 Quite Low
Adhesions 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After interaction with the CC chemokine receptor 5 (CCR5), it activates memory T cells and monocytes, which are the predominant cells in the synovial tissue of patients with PMR [16].
Positive_regulation (activates) of CCR5 Binding (interaction) of in memory T cells associated with chemokine and polymyalgia rheumatica
1) Confidence 0.47 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128892 Disease Relevance 0.97 Pain Relevance 0.16
After interaction with the CC chemokine receptor 5 (CCR5), it activates memory T cells and monocytes, which are the predominant cells in the synovial tissue of patients with PMR [16].
Positive_regulation (activates) of chemokine receptor 5 Binding (interaction) of in memory T cells associated with chemokine and polymyalgia rheumatica
2) Confidence 0.41 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128892 Disease Relevance 0.97 Pain Relevance 0.16
After interaction with the CC chemokine receptor 5 (CCR5), it activates memory T cells and monocytes, which are the predominant cells in the synovial tissue of patients with PMR [16].
Positive_regulation (activates) of CCR5 in monocytes Binding (interaction) of in memory T cells associated with chemokine and polymyalgia rheumatica
3) Confidence 0.16 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128892 Disease Relevance 0.97 Pain Relevance 0.16
After interaction with the CC chemokine receptor 5 (CCR5), it activates memory T cells and monocytes, which are the predominant cells in the synovial tissue of patients with PMR [16].
Positive_regulation (activates) of chemokine receptor 5 in monocytes Binding (interaction) of in memory T cells associated with chemokine and polymyalgia rheumatica
4) Confidence 0.14 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128892 Disease Relevance 0.97 Pain Relevance 0.16

General Comments

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