INT171972

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Context Info
Confidence 0.08
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tnfsf11, Il6) extracellular region (Tnfsf11, Il6) cell differentiation (Tnfsf11)
plasma membrane (Tnfsf11) intracellular (Tnfsf11) cytoplasm (Tnfsf11)
Anatomy Link Frequency
dendritic cells 2
Tnfsf11 (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 14 100.00 Very High Very High Very High
rheumatoid arthritis 33 80.24 Quite High
Inflammation 36 50.00 Quite Low
Arthritis 18 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Etanercept 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 33 80.24 Quite High
Disease 7 68.56 Quite High
Infection 1 48.76 Quite Low
Targeted Disruption 1 44.96 Quite Low
INFLAMMATION 29 40.56 Quite Low
Congenital Anomalies 1 40.00 Quite Low
Arthritis 25 35.24 Quite Low
Hypercalcemia 13 23.36 Low Low
Osteoporosis 18 19.60 Low Low
Adhesions 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, RANKL induces the production of proinflammatory cytokines, such as IL-1 and IL-6, and of cytokines that stimulate and induce differentiation of T cells, such as IL-12 and IL-15, by the antigen-presenting dendritic cells [65,66].
RANKL Positive_regulation (induces) of Gene_expression (production) of IL-6 in dendritic cells associated with cytokine
1) Confidence 0.08 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128900 Disease Relevance 0.21 Pain Relevance 0.21

General Comments

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