INT171976

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Context Info
Confidence 0.01
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.37
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18) extracellular region (Il18) cytoplasm (Il18)
Anatomy Link Frequency
osteoblast 3
stromal cells 1
Il18 (Mus musculus)
IFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 2 99.36 Very High Very High Very High
rheumatoid arthritis 66 92.16 High High
Arthritis 36 73.20 Quite High
Inflammation 72 69.28 Quite High
antagonist 4 50.08 Quite High
cytokine 28 45.84 Quite Low
Infliximab 2 18.20 Low Low
Etanercept 2 16.40 Low Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 36 100.00 Very High Very High Very High
Frailty 4 99.36 Very High Very High Very High
Rheumatoid Arthritis 66 92.16 High High
Arthritis 50 73.20 Quite High
Multiple Myeloma 2 62.20 Quite High
INFLAMMATION 58 46.88 Quite Low
Hypercalcemia 26 28.16 Quite Low
Synovitis 2 25.96 Quite Low
Osteolysis 2 5.12 Low Low
Disease 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-18 is produced by osteoblast/stromal cells and sustains Th1 response by upregulating the expression of IFN-?
IL-18 Positive_regulation (upregulating) of Gene_expression (expression) of IFN in osteoblast associated with osteoporosis
1) Confidence 0.01 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128900 Disease Relevance 0.69 Pain Relevance 0.32
IL-18 is produced by osteoblast/stromal cells and sustains Th1 response by upregulating the expression of IFN-?
IL-18 Positive_regulation (upregulating) of in stromal cells Gene_expression (expression) of IFN in osteoblast associated with osteoporosis
2) Confidence 0.00 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128900 Disease Relevance 0.69 Pain Relevance 0.32

General Comments

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