INT171995

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Context Info
Confidence 0.35
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 1.16
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (PTH1R) plasma membrane (PTH1R) nucleus (PTH1R)
intracellular (PTH1R) cytoplasm (PTH1R) signal transducer activity (PTH1R)
Anatomy Link Frequency
plasma 2
parathyroid 2
blood 1
vein 1
PTH1R (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 58 100.00 Very High Very High Very High
ketamine 2 93.68 High High
Osteoarthritis 109 66.40 Quite High
COX2 6 58.56 Quite High
anesthesia 4 13.12 Low Low
cytokine 14 10.08 Low Low
Inflammation 76 5.00 Very Low Very Low Very Low
Arthritis 32 5.00 Very Low Very Low Very Low
Bioavailability 12 5.00 Very Low Very Low Very Low
Inflammatory stimuli 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fat Embolism 57 100.00 Very High Very High Very High
Osteoporosis 36 99.84 Very High Very High Very High
Aspergillus Infection 1 93.80 High High
Disease 41 92.00 High High
Diabetes Insipidus 1 72.40 Quite High
Chondrodysplasia 1 67.12 Quite High
Osteoarthritis 122 66.40 Quite High
Congenital Anomalies 7 62.24 Quite High
Hypercalcemia 2 62.24 Quite High
Spontaneous Fractures 1 34.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To demonstrate specificity of binding of mouse anti-rabbit PTH1R in control experiments, sections were incubated (a) without primary antibody or, instead of primary antibody, (b) mouse IgG1 with irrelevant specificity (Aspergillus niger glucose oxidase; Dako) was used at the same concentration as the primary antibody.
PTH1R Binding (binding) of associated with aspergillus infection
1) Confidence 0.35 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2867974 Disease Relevance 0.23 Pain Relevance 0.03
PTHR-1-ligand interactions and their mechanism of action in vertebrates are well understood.
PTHR-1 Binding (interactions) of
2) Confidence 0.29 Published 2008 Journal BMC Evol Biol Section Body Doc Link PMC2396169 Disease Relevance 0.34 Pain Relevance 0
, product size 88 bp; parathyroid hormone receptor 1(PTHR1), sense (5?
PTHR1 Binding (receptor) of in parathyroid
3) Confidence 0.23 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2579486 Disease Relevance 0 Pain Relevance 0
In 24 rabbits, PFE was induced by intravenous injection through the ear vein with a 1-mL syringe loaded with 0.2 mL dose of linoleic acid (cis-9, cis-12- octadecadienoic acid, 99% purity; Sigma, St.
PFE Binding (induced) of in vein associated with cva
4) Confidence 0.14 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526389 Disease Relevance 0.41 Pain Relevance 0.22
As our studies showed that plasma containing bioavailable PFE constituents and PFE-derived metabolites was a potent inhibitor of COX activity ex vivo, we determined its effect on IL-1?
PFE Binding (metabolites) of in plasma
5) Confidence 0.12 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2438359 Disease Relevance 0 Pain Relevance 0
As our studies showed that plasma containing bioavailable PFE constituents and PFE-derived metabolites was a potent inhibitor of COX activity ex vivo, we determined its effect on IL-1?
PFE Binding (plasma) of in plasma
6) Confidence 0.12 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2438359 Disease Relevance 0 Pain Relevance 0.03
Incubation with plasma samples obtained before the oral ingestion of PFE suppressed the COX-1 activity by 14.85 ± 2.41% while incubation with blood samples obtained after supplementation with PFE suppressed the COX-1 activity by 21.47 ± 3.64%.
PFE Binding (supplementation) of in blood
7) Confidence 0.12 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2438359 Disease Relevance 0 Pain Relevance 0.03
Preliminary data from such a study showed a suggestive linkage of the parathyroid hormone receptor type 1 to osteoporosis [131].
parathyroid hormone receptor type 1 Binding (linkage) of in parathyroid associated with osteoporosis
8) Confidence 0.08 Published 2001 Journal Arthritis Res Section Body Doc Link PMC128904 Disease Relevance 0.19 Pain Relevance 0

General Comments

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