INT172096

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Context Info
Confidence 0.01
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.32
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-E)
Anatomy Link Frequency
T-cell 3
HLA-E (Homo sapiens)
Il27ra (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 95.40 Very High Very High Very High
rheumatoid arthritis 68 86.40 High High
tolerance 6 84.64 Quite High
Arthritis 15 79.60 Quite High
Osteoarthritis 1 8.96 Low Low
Kinase C 12 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
abatacept 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
General Immunology 4 98.24 Very High Very High Very High
Disease 35 96.08 Very High Very High Very High
INFLAMMATION 9 95.40 Very High Very High Very High
Targeted Disruption 9 94.48 High High
Rheumatoid Arthritis 68 86.40 High High
Arthritis 17 80.64 Quite High
Autoimmune Disease 31 72.08 Quite High
Experimental Arthritis 1 56.48 Quite High
Congenital Anomalies 3 46.64 Quite Low
Osteoarthritis 1 8.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The new model is based on a transgene encoded T-cell receptor (TCR) that recognizes a self-component in the context of the mouse MHC class II molecule I-Ag7 (formerly known as I-ANOD).
MHC Binding (recognizes) of T-cell receptor in T-cell
1) Confidence 0.01 Published 2000 Journal Arthritis Res Section Body Doc Link PMC129986 Disease Relevance 0.98 Pain Relevance 0.39
Signal 1 is delivered by the T-cell receptor (TCR) recognizing the antigenic peptide within the context of the major histocompatibility complex (MHC) molecule.
MHC Binding (recognizing) of T-cell receptor in T-cell
2) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582810 Disease Relevance 0.17 Pain Relevance 0.04
Signal 1 is delivered by the T-cell receptor (TCR) recognizing the antigenic peptide within the context of the major histocompatibility complex (MHC) molecule.
MHC Binding (recognizing) of T-cell receptor in T-cell
3) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582810 Disease Relevance 0.17 Pain Relevance 0.04

General Comments

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