INT172125

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Context Info
Confidence 0.17
First Reported 2000
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.12
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf11b) extracellular region (Tnfrsf11b) proteinaceous extracellular matrix (Tnfrsf11b)
extracellular matrix organization (Tnfrsf11b)
Tnfrsf11b (Mus musculus)
Tnfrsf11a (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 1 87.04 High High
withdrawal 2 79.28 Quite High
Inflammation 87 65.76 Quite High
rheumatoid arthritis 22 65.32 Quite High
Infliximab 1 54.24 Quite High
Etanercept 2 53.64 Quite High
cytokine 46 50.56 Quite High
Arthritis 3 44.92 Quite Low
antagonist 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 19 96.80 Very High Very High Very High
Necrosis 5 89.36 High High
Cancer 9 89.00 High High
Postmenopausal Osteoporosis 6 83.04 Quite High
Targeted Disruption 2 81.68 Quite High
Osteopetrosis 1 76.08 Quite High
INFLAMMATION 86 65.76 Quite High
Rheumatoid Arthritis 22 65.32 Quite High
Disease 27 63.24 Quite High
Autoimmune Disease 4 60.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor, functions as a soluble decoy receptor to RANKL and competes with RANK for RANKL binding.
OPG Binding (binding) of RANK
1) Confidence 0.17 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1308846 Disease Relevance 0.79 Pain Relevance 0.07
Osteoprotegerin (OPG) is a natural decoy receptor that binds to RANK ligand and prevents its interaction with RANK [42].
Osteoprotegerin Binding (binds) of RANK
2) Confidence 0.14 Published 2000 Journal Arthritis Res Section Body Doc Link PMC129996 Disease Relevance 0.53 Pain Relevance 0.22
Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor, functions as a soluble decoy receptor to RANKL and competes with RANK for RANKL binding.
Osteoprotegerin Binding (binding) of RANK
3) Confidence 0.04 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1308846 Disease Relevance 0.80 Pain Relevance 0.10

General Comments

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