INT172145

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Context Info
Confidence 0.04
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL10, CSF2) extracellular region (IL10, CSF2) intracellular (IL10)
cell-cell signaling (IL10) response to stress (IL10)
Anatomy Link Frequency
monocytes 2
IL10 (Homo sapiens)
CSF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 53 100.00 Very High Very High Very High
fibrosis 1 94.76 High High
chemokine 4 93.60 High High
Arthritis 37 88.48 High High
rheumatoid arthritis 88 81.92 Quite High
Inflammation 37 61.04 Quite High
antagonist 10 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 1 94.76 High High
Experimental Arthritis 6 89.52 High High
Autoimmune Disease 3 86.80 High High
Rheumatoid Arthritis 91 81.92 Quite High
Arthritis 36 81.44 Quite High
Hypercalcemia 2 75.04 Quite High
INFLAMMATION 37 61.04 Quite High
Disease 20 5.84 Low Low
Synovitis 7 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Accordingly, IL-10 reduces HLA-DR expression and antigen presentation in monocytes [87] and inhibits the production of proinflammatory cytokines, GM-CSF and Fc?
IL-10 Negative_regulation (inhibits) of Gene_expression (production) of GM-CSF in monocytes associated with cytokine
1) Confidence 0.04 Published 2000 Journal Arthritis Res Section Body Doc Link PMC130001 Disease Relevance 0.69 Pain Relevance 0.59

General Comments

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