INT172370

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Context Info
Confidence 0.34
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.75
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (MCPH1) intracellular (MCPH1) microtubule organizing center (MCPH1)
cytoplasm (MCPH1)
MCPH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 2 69.00 Quite High
Inflammation 16 61.20 Quite High
adenocard 5 30.80 Quite Low
Inflammatory response 3 21.04 Low Low
palliative 1 5.20 Low Low
antagonist 12 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
Glutamate 7 5.00 Very Low Very Low Very Low
corticosteroid 6 5.00 Very Low Very Low Very Low
Serotonin 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 154 100.00 Very High Very High Very High
Hypertrophy 36 99.76 Very High Very High Very High
Pulmonary Hypertension 150 99.38 Very High Very High Very High
Toxicity 4 97.52 Very High Very High Very High
Metastasis 9 96.80 Very High Very High Very High
Cold Sores 36 93.52 High High
Sepsis 10 89.32 High High
Colon Cancer 16 88.88 High High
Intellectual Impairment 6 86.92 High High
Disease 9 85.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MCPH1 and condensin II interact in vivo, mediated by the CAPG2 subunit of condensin II [36].

14q32.33 deletion

MCPH1 Binding (interact) of
1) Confidence 0.34 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2892449 Disease Relevance 0.53 Pain Relevance 0
Prognostic factors such as grade, metastases and tumour location are registered in the DVCR and the registry may be used for collection of cases for studies; both of cases that were treated following the recommendation for MCT treatment and cases that were not.
MCT Binding (recommendation) of associated with cancer and metastasis
2) Confidence 0.32 Published 2010 Journal Acta Vet Scand Section Body Doc Link PMC2823750 Disease Relevance 1.36 Pain Relevance 0
These are lipids with both LCT and MCT bonded to the glycerol backbone (Fig. 2).
MCT Binding (bonded) of
3) Confidence 0.06 Published 1999 Journal Crit Care Section Body Doc Link PMC137235 Disease Relevance 0.46 Pain Relevance 0.06
These are lipids with both LCT and MCT bonded to the glycerol backbone (Fig. 2).
MCT Binding (lipids) of
4) Confidence 0.06 Published 1999 Journal Crit Care Section Body Doc Link PMC137235 Disease Relevance 0.46 Pain Relevance 0.06
Crystal structure studies [47] of MCT with both enzymes show that the thymine moiety of MCT binds similarly to deoxythymidine, with the conformationally restricted bicyclo[3.1.0]hexane mimicking the sugar moiety.
MCT Binding (binds) of
5) Confidence 0.03 Published 2003 Journal J Biomed Biotechnol Section Body Doc Link PMC179761 Disease Relevance 1.09 Pain Relevance 0
To study whether in vivo modulation of Cav-1 expression could affect the development of PAH and RV hypertrophy, rats were injected with MCT, followed by a daily injection of (1) saline, (2) a peptide corresponding to the homeodomain of the Drosophila transcription factor antennapedia (AP; 2.5?
MCT Binding (injected) of associated with hypertrophy and pulmonary hypertension
6) Confidence 0.02 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 0.85 Pain Relevance 0

General Comments

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