INT172411

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Context Info
Confidence 0.22
First Reported 2002
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.93
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (SV2A) endoplasmic reticulum (SV2A) cytoplasm (SV2A)
Anatomy Link Frequency
synaptic vesicle 3
SV2A (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 24 100.00 Very High Very High Very High
Botox 4 93.08 High High
cytokine 2 88.80 High High
Inflammation 5 88.44 High High
Neuropeptide 6 86.52 High High
GABAergic 7 80.96 Quite High
Neurotransmitter 35 73.00 Quite High
Calcitonin gene-related peptide 11 57.76 Quite High
Glutamate 25 45.80 Quite Low
gABA 49 45.36 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 88.44 High High
Muscle Hypertonia 4 80.56 Quite High
Critical Illness 13 75.96 Quite High
Heart Rate Under Development 31 67.20 Quite High
Cerebral Palsy 16 65.12 Quite High
Spasticity 50 63.48 Quite High
Foot Deformities 2 62.64 Quite High
Infection 6 51.20 Quite High
Syndrome 10 50.92 Quite High
Movement Disorders 4 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, then co-labeled for SP and synaptic vesicle 2 (SV2) protein or synaptophysin (Syn), and studied by immunofluorescence (Fig. 1A).
Regulation (labeled) of SV2 in synaptic vesicle associated with substance p
1) Confidence 0.22 Published 2008 Journal Biological Procedures Online Section Body Doc Link PMC2683550 Disease Relevance 0.09 Pain Relevance 0.52
It is taken up into the end plate via the high affinity synaptic vesicle protein 2 (SV2) which is up regulated in active neurons.
Regulation (regulated) of SV2 in synaptic vesicle
2) Confidence 0.04 Published 2009 Journal Ulster Med J Section Body Doc Link PMC2773587 Disease Relevance 0.27 Pain Relevance 0.05
It is taken up into the end plate via the high affinity synaptic vesicle protein 2 (SV2) which is up regulated in active neurons.
Regulation (regulated) of synaptic vesicle protein 2 in synaptic vesicle
3) Confidence 0.04 Published 2009 Journal Ulster Med J Section Body Doc Link PMC2773587 Disease Relevance 0.32 Pain Relevance 0.05
A normal SvO2 value, for instance, does not rule out an impaired oxygen supply to individual organs [16].


Regulation (value) of SvO2
4) Confidence 0.00 Published 2002 Journal Crit Care Section Body Doc Link PMC137397 Disease Relevance 0.25 Pain Relevance 0

General Comments

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