INT172465

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Context Info
Confidence 0.41
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Rab27a, Rab27b) GTPase activity (Rab27a, Rab27b) endosome (Rab27a)
intracellular (Rab27a) cytoplasm (Rab27b) pigmentation (Rab27a)
Anatomy Link Frequency
mast cell 2
Rab27a (Mus musculus)
Rab27b (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 12 99.76 Very High Very High Very High
cytokine 2 78.52 Quite High
imagery 8 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Choroideremia 15 97.52 Very High Very High Very High
Targeted Disruption 190 94.32 High High
Hypersensitivity 12 84.08 Quite High
Disease 8 76.56 Quite High
Anaphylaxis 20 70.40 Quite High
Syndrome 13 69.60 Quite High
Sprains And Strains 6 52.88 Quite High
Piebaldism 4 37.60 Quite Low
Hemorrhagic Diathesis 2 17.04 Low Low
Retina Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that Rab27b and to a lesser extent Rab27a are associated with serotonin-containing mast cell secretory granules.
Rab27a Binding (associated) of Rab27b in mast cell associated with serotonin
1) Confidence 0.41 Published 2007 Journal Traffic (Copenhagen, Denmark) Section Body Doc Link PMC2063611 Disease Relevance 0.54 Pain Relevance 0.14
These results suggest that Rab27b and to a lesser extent Rab27a are associated with serotonin-containing mast cell secretory granules.
Rab27a Binding (associated) of Rab27b in mast cell associated with serotonin
2) Confidence 0.41 Published 2007 Journal Traffic (Copenhagen, Denmark) Section Body Doc Link PMC2063611 Disease Relevance 0.54 Pain Relevance 0.14
Our recent finding that Rab27b shows functional redundancy with Rab27a further suggests that Rab27a-related Rabs may be involved in CHM [28].
Rab27a Binding (redundancy) of Rab27b associated with choroideremia
3) Confidence 0.30 Published 2002 Journal BMC Cell Biol Section Body Doc Link PMC137576 Disease Relevance 0.63 Pain Relevance 0

General Comments

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