INT172620

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Context Info
Confidence 0.09
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CREBBP) small molecule metabolic process (CREBBP) protein complex assembly (CREBBP)
DNA binding (CREBBP) cytoplasm (CREBBP) signal transducer activity (CREBBP)
CREBBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 5 45.68 Quite Low
Inflammation 7 16.00 Low Low
agonist 33 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 2 55.24 Quite High
INFLAMMATION 12 45.28 Quite Low
Obesity 17 42.80 Quite Low
Familial Partial Lipodystrophy 1 38.40 Quite Low
Metabolic Syndrome 1 32.00 Quite Low
Dyslipidemia /

Combined Dyslipidemia

1 29.04 Quite Low
Wound Healing 1 25.48 Quite Low
Liver Cancer 2 24.52 Low Low
Hepatomegaly 1 22.88 Low Low
Syndrome 1 20.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transrepression occurs through sequestration of the coactivators CBP and SRC-1 by the PPAR/RXR heterodimers, preventing their utilization in other signaling pathways [62].
Localization (sequestration) of CBP
1) Confidence 0.09 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0.06 Pain Relevance 0
Both p300 and CBP can mediate acetylation of Rch1 and importin-?
Localization (importin) of CBP
2) Confidence 0.02 Published 2002 Journal Genome Biol Section Body Doc Link PMC139359 Disease Relevance 0 Pain Relevance 0

General Comments

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