INT172697

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Context Info
Confidence 0.24
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adora2b) signal transducer activity (Adora2b)
Anatomy Link Frequency
small intestine 1
Adora2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 38 91.80 High High
Neuropeptide 3 80.00 Quite High
Nicotine 1 74.04 Quite High
alcohol 1 73.48 Quite High
Morphine 2 73.12 Quite High
cocaine 105 72.72 Quite High
Neurotransmitter 6 66.40 Quite High
Nucleus accumbens 35 50.00 Quite Low
long-term potentiation 1 49.36 Quite Low
substance P 2 42.48 Quite Low
Disease Link Frequency Relevance Heat
Aids-related Complex 11 78.36 Quite High
Drug Dependence 2 39.44 Quite Low
Cocaine Dependence 10 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Osteogenic Sarcomas 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Network analysis was conducted using the set of confirmed mPFC gene expression changes, and revealed that Cart, NPY, Nr4a1, Fos, Egr1, Adora2b and Drd5 all interact (directly or indirectly) with the MAPK/ERK pathway.
Adora2b Binding (interact) of
1) Confidence 0.24 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2837051 Disease Relevance 0.08 Pain Relevance 0.25
Using either ligand binding, functional studies, or molecular techniques, A1, A2A, A2B, and A3 receptors have been identified within the rat small intestine [7-10].
A2B Binding (binding) of in small intestine
2) Confidence 0.13 Published 2002 Journal BMC Neurosci Section Body Doc Link PMC139982 Disease Relevance 0 Pain Relevance 0.37

General Comments

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