INT172806

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.26
First Reported 2002
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.64
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ISL1) cytoplasm (ISL1)
Anatomy Link Frequency
neuronal 1
Islets of Langerhans 1
beta cell 1
motor neuron 1
ISL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 91.40 High High
Action potential 17 85.20 High High
gABA 10 81.92 Quite High
conotoxin 24 67.72 Quite High
Spinal cord 39 66.68 Quite High
antagonist 17 27.92 Quite Low
metalloproteinase 17 27.72 Quite Low
tetrodotoxin 20 5.00 Very Low Very Low Very Low
Nerve growth factor 11 5.00 Very Low Very Low Very Low
tolerance 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Islet Cell Adenoma 29 100.00 Very High Very High Very High
Pancreatic Cancer 27 100.00 Very High Very High Very High
Alzheimer's Dementia 12 98.26 Very High Very High Very High
Diabetes Mellitus 150 97.56 Very High Very High Very High
Toxicity 24 95.16 Very High Very High Very High
INFLAMMATION 32 91.40 High High
Aging 10 89.44 High High
Stress 69 89.00 High High
Hyperinsulinism 9 87.12 High High
Injury 35 79.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
1000, Covance, Princeton, NJ), retrograde transport (CTB, Invitrogen, Carlsbad, CA) or the motor neuron lineage markers Islet1 (Isl-1; 1?
Localization (transport) of Isl-1 in motor neuron
1) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912300 Disease Relevance 0.22 Pain Relevance 0.03
These putative membrane/secreted protein encoding genes identified for pancreatic cancer and islet cell tumors were then examined using unsupervised hierarchical clustering in the context of a diverse collection of normal human tissues.
Spec (examined) Localization (secreted) of islet associated with islet cell adenoma and pancreatic cancer
2) Confidence 0.07 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1824711 Disease Relevance 0.85 Pain Relevance 0
-cell glucagon secretion by neuronal factors and by paracrine factors from neighbouring cells, including the important islet hormone insulin.
Localization (secretion) of islet in neuronal
3) Confidence 0.04 Published 2007 Journal PLoS Biology Section Abstract Doc Link PMC1868042 Disease Relevance 0.10 Pain Relevance 0.10
Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans

Glucagon, secreted from pancreatic islet ?

Localization (secreted) of islet in Islets of Langerhans
4) Confidence 0.03 Published 2007 Journal PLoS Biology Section Title Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.07
Amylin, also termed islet amyloid polypeptide (IAPP) is a 37 amino acid polypeptide co-synthesized, co-packaged, and co-secreted by the islet beta cell with insulin.
Localization (secreted) of islet in beta cell associated with alzheimer's dementia
5) Confidence 0.01 Published 2002 Journal Cardiovasc Diabetol Section Body Doc Link PMC140143 Disease Relevance 1.47 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox