INT172815

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Context Info
Confidence 0.65
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.86
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Cand1) nucleus (Cand1)
Anatomy Link Frequency
endothelial cells 1
heart 1
Cand1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Tetrahydrobiopterin 5 68.72 Quite High
rheumatoid arthritis 16 65.72 Quite High
adenocard 3 50.80 Quite High
addiction 6 47.08 Quite Low
Bioavailability 1 46.56 Quite Low
Inflammation 35 40.96 Quite Low
agonist 4 13.08 Low Low
metalloproteinase 14 5.00 Very Low Very Low Very Low
lidocaine 10 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 61 99.98 Very High Very High Very High
Diabetes Mellitus 166 98.80 Very High Very High Very High
Stress 70 89.84 High High
Hyperglycemia 9 88.80 High High
Coronary Heart Disease 6 81.68 Quite High
Myocardial Infarction 5 80.24 Quite High
Obesity 17 70.04 Quite High
Hyperhomocysteinemia 3 66.64 Quite High
Rheumatoid Arthritis 16 65.72 Quite High
Atherosclerosis 32 62.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stepp and colleagues were able to demonstrate a 4 fold increase in O2' and an 8 fold increase in O2' when endothelial cells were exposed to native LDL-C and mmLDL-C respectively.
Gene_expression (exposed) of C and in endothelial cells
1) Confidence 0.65 Published 2002 Journal Cardiovasc Diabetol Section Body Doc Link PMC140143 Disease Relevance 0.66 Pain Relevance 0.06
None of the foregoing treatments significantly affected serum triacylglycerol, HDL-C and VLDL-C levels.
Gene_expression (levels) of C and associated with disorder of lipid metabolism
2) Confidence 0.65 Published 2005 Journal Lipids Health Dis Section Body Doc Link PMC1266394 Disease Relevance 0.45 Pain Relevance 0
We did not find any significant change in HDL-C and LDL-C concentrations among four groups.
Gene_expression (concentrations) of C and associated with disorder of lipid metabolism
3) Confidence 0.65 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663461 Disease Relevance 0.58 Pain Relevance 0.03
Addition of Isoprenaline to the electrically paced (5 Hz) heart caused marked elevations of the cMyBP-C and cTnI phosphorylation levels, but did not result in a further significant increase in MLC-2 phosphorylation.
Gene_expression (levels) of C and in heart
4) Confidence 0.65 Published 2007 Journal Basic Res Cardiol Section Body Doc Link PMC2780643 Disease Relevance 0 Pain Relevance 0.03
These experiments indicate that the PKA-sensitive phosphorylation sites on cMyBP-C and/or cTnI were not saturated under basal conditions even in the Isoprenaline group.
Gene_expression (/) of C and
5) Confidence 0.65 Published 2007 Journal Basic Res Cardiol Section Body Doc Link PMC2780643 Disease Relevance 0.16 Pain Relevance 0

General Comments

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