INT172829

Context Info Confidence 0.00 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 2.06 Pain Relevance 0.17

cytoplasm (Nfkb1, ISYNA1) isomerase activity (ISYNA1) mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1) cytosol (Nfkb1)

Anatomy Link Frequency beta cell 1 Nfkb1 (Mus musculus) ISYNA1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 26 84.08 Inflammatory mediators 2 67.92 cytokine 2 64.00 cva 3 43.72 Pain 3 42.60 metalloproteinase 14 5.00 Tetrahydrobiopterin 5 5.00 tolerance 5 5.00 ischemia 2 5.00 bradykinin 2 5.00

Disease Link Frequency Relevance Heat Stress 68 100.00 Diabetes Mellitus 136 99.68 Apoptosis 10 99.68 Adhesions 4 90.80 Alzheimer's Dementia 12 90.08 INFLAMMATION 28 84.08 Acute-phase Reaction 2 76.84 Prediabetic State 36 72.44 Insulin Resistance 50 72.28 Metabolic Syndrome 49 72.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NFkappa B is associated with redox stress and the isoform inducible iNOS in the apoptosis of the beta cell in both T1DM and T2DM.

NFkappa B Binding (associated) of iNOS in beta cell associated with stress, diabetes mellitus and apoptosis

1) Confidence 0.00 Published 2002 Journal Cardiovasc Diabetol Section Body Doc Link PMC140143 Disease Relevance 2.06 Pain Relevance 0.17

General Comments

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