INT172857

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Context Info
Confidence 0.36
First Reported 2003
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.86
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Bad) cell proliferation (Bad) cytosol (Bad)
mitochondrion (Bad) cytoplasm (Bad)
Bad (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 6 100.00 Very High Very High Very High
agonist 1 73.20 Quite High
withdrawal 1 70.24 Quite High
metalloproteinase 1 48.00 Quite Low
cINOD 18 32.80 Quite Low
COX-2 inhibitor 10 17.92 Low Low
aspirin 8 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 5 100.00 Very High Very High Very High
Apoptosis 66 96.40 Very High Very High Very High
Prostate Cancer 40 91.92 High High
Pancreatic Cancer 84 80.88 Quite High
Cancer 101 69.76 Quite High
Adhesions 3 67.52 Quite High
Repression 1 13.28 Low Low
Adenocarcinoma 8 5.00 Very Low Very Low Very Low
Metastasis 5 5.00 Very Low Very Low Very Low
Colon Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BAD, bcl-xl/bcl-2- antagonist causing cell death, was initially identified in a yeast two hybrid screen interacting with Bcl-2 or Bcl-xl [10].
BAD Binding (interacting) of associated with antagonist and death
1) Confidence 0.36 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2704953 Disease Relevance 1.64 Pain Relevance 0.12
Phosphorylation of Bad results in its binding to 14-3-3 proteins and prevents it binding to Bcl-2 and Bcl-xL.
Bad Binding (binding) of
2) Confidence 0.05 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149414 Disease Relevance 1.21 Pain Relevance 0

General Comments

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