INT172860

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Context Info
Confidence 0.09
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Alox8) intracellular (Alox8) cytoplasm (Alox8)
Alox8 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 18 5.00 Very Low Very Low Very Low
COX-2 inhibitor 10 5.00 Very Low Very Low Very Low
aspirin 8 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 76 99.06 Very High Very High Very High
Pancreatic Cancer 84 86.80 High High
Targeted Disruption 4 82.36 Quite High
Prostate Cancer 6 69.52 Quite High
Metastasis 5 59.76 Quite High
Apoptosis 39 56.84 Quite High
Carcinosarcoma 1 52.72 Quite High
Skin Cancer 2 41.28 Quite Low
Adenocarcinoma 8 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While the function of 8-HPETE and 8-HETE are unknown, their importance in tumor promoter-elicited events is suggested by the finding that application of the lipoxygenase inhibitor, eicosatetraenoic acid maximally inhibits tumor promotion when applied at the time of maximum induction of 8-lipoxygenase [26,27].
Positive_regulation (induction) of 8-lipoxygenase associated with cancer
1) Confidence 0.09 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149414 Disease Relevance 1.08 Pain Relevance 0

General Comments

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