INT172864

Context Info Confidence 0.05 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.04 Pain Relevance 0

signal transduction (Ltb4r1) plasma membrane (Ltb4r1) signal transducer activity (Ltb4r1)

Ltb4r1 (Mus musculus)

Pain Link Frequency Relevance Heat COX-2 inhibitor 10 45.60 cINOD 18 35.04 Inflammation 3 33.04 aspirin 8 5.00 cytokine 3 5.00 antagonist 3 5.00 Paracetamol 1 5.00 metalloproteinase 1 5.00

Disease Link Frequency Relevance Heat Pancreatic Cancer 84 98.16 Apoptosis 39 95.20 Cancer 76 88.68 Immunotherapy Of Cancer 2 67.16 Colon Cancer 5 40.60 INFLAMMATION 5 33.04 Adenocarcinoma 8 5.00 Prostate Cancer 6 5.00 Metastasis 5 5.00 Death 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The anti-pancreatic cancer activity of this extract is probably mediated through inhibition of LOX activity, since it inhibits LTB4 secretion.

Negative_regulation (inhibits) of Localization (secretion) of LTB4 associated with pancreatic cancer

1) Confidence 0.05 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149414 Disease Relevance 1.04 Pain Relevance 0

General Comments

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