INT172867

Context Info Confidence 0.04 First Reported 2003 Last Reported 2003 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.23 Pain Relevance 0

peptidase activity (Lta4h) nucleus (Lta4h) cytoplasm (Lta4h)

Lta4h (Mus musculus)

Pain Link Frequency Relevance Heat Paracetamol 1 39.12 cINOD 18 37.36 COX-2 inhibitor 10 5.00 aspirin 8 5.00 cytokine 3 5.00 Inflammation 3 5.00 antagonist 3 5.00 metalloproteinase 1 5.00

Disease Link Frequency Relevance Heat Adhesions 3 97.96 Anaphylaxis 1 75.84 Cancer 76 58.88 Prostate Cancer 6 38.48 Colon Cancer 5 15.76 Targeted Disruption 4 13.40 Pancreatic Cancer 84 10.68 Apoptosis 39 5.00 Adenocarcinoma 8 5.00 Metastasis 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

LTC4 synthase catalyzes the conjugation of LTA4 with glutathione to form LTC4 at the nuclear envelope.

LTA4 Binding (conjugation) of

1) Confidence 0.04 Published 2003 Journal Mol Cancer Section Body Doc Link PMC149414 Disease Relevance 0.23 Pain Relevance 0

General Comments

This test has worked.