INT173056

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Context Info
Confidence 0.24
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NRP2, NRP1) cell adhesion (NRP2, NRP1) plasma membrane (NRP2, NRP1)
cytosol (NRP1) signal transduction (NRP1) extracellular region (NRP1)
NRP2 (Homo sapiens)
NRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 10 79.00 Quite High
dorsal root ganglion 1 44.04 Quite Low
Chronic low back pain 9 5.00 Very Low Very Low Very Low
Nerve growth factor 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
backache 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 78 94.32 High High
Pancreatic Cancer 81 83.92 Quite High
Shock 4 61.04 Quite High
Pressure And Volume Under Development 1 55.60 Quite High
Metastasis 25 52.64 Quite High
Hypoxia 53 50.00 Quite Low
Ganglion Cysts 1 44.04 Quite Low
Apoptosis 2 17.52 Low Low
Recurrence 2 6.40 Low Low
Low Back Pain 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The neuropilins consist of two members; NRP1 which is thought to be the principal receptor for sema3A and NRP2 which is thought to be the principal receptor for sema3F [36-39].
NRP2 Binding (receptor) of NRP1
1) Confidence 0.24 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875625 Disease Relevance 0.06 Pain Relevance 0.04
Neuropilin-2 is also able to bind VEGF-A165, but unlike neuropilin-1, it also interacts with VEGF-A145 [70,72,73].
Neuropilin-2 Binding (interacts) of neuropilin-1
2) Confidence 0.02 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 0.55 Pain Relevance 0

General Comments

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