INT173057

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Context Info
Confidence 0.24
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.49
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HIF1A, VEGFA) cell differentiation (HIF1A) signal transducer activity (HIF1A)
extracellular space (VEGFA) signal transduction (HIF1A) growth (VEGFA)
HIF1A (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 77.88 Quite High
cytokine 7 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 81 99.76 Very High Very High Very High
Cancer 77 94.00 High High
Hypoxia 50 82.64 Quite High
Pancreatitis 3 77.88 Quite High
Disease 3 35.76 Quite Low
Metastasis 25 30.12 Quite Low
Reprotox - General 3 1 25.84 Quite Low
Fibroadenoma 1 24.96 Low Low
Adenoma 1 22.12 Low Low
Prostatic Intraepithelial Neoplasia 1 21.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro all pancreatic cancer cell lines increased VEGF production under low oxygen levels by highly specific activation of HIF-1 DNA binding activity to the VEGF promotor [43].
Positive_regulation (activation) of HIF-1 Positive_regulation (increased) of Gene_expression (production) of VEGF associated with pancreatic cancer
1) Confidence 0.24 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 1.49 Pain Relevance 0.08

General Comments

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