INT173062

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Context Info
Confidence 0.04
First Reported 2003
Last Reported 2003
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HIF1A, VHLL) cell differentiation (HIF1A) signal transduction (HIF1A)
nucleolus (HIF1A) transcription factor binding (HIF1A) cytoplasm (HIF1A)
HIF1A (Homo sapiens)
VHLL (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 2 93.32 High High
cytokine 14 5.00 Very Low Very Low Very Low
Chronic pancreatitis 6 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Tumor 2 94.00 High High
Cancer 154 92.08 High High
Carcinoma 2 90.40 High High
Hypoxia 100 77.60 Quite High
Pancreatic Cancer 162 29.44 Quite Low
Metastasis 50 5.00 Very Low Very Low Very Low
Adenocarcinoma 20 5.00 Very Low Very Low Very Low
Solid Tumor 10 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low
Pancreatitis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As the VHL protein is a subunit in the multimeric E3 ubiquitin ligase complex, its binding to the ODD regions of HIF-1?
HIF-1 Binding (complex) of VHL protein
1) Confidence 0.04 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 0.63 Pain Relevance 0.05
As the VHL protein is a subunit in the multimeric E3 ubiquitin ligase complex, its binding to the ODD regions of HIF-1?
HIF-1 Binding (binding) of VHL protein
2) Confidence 0.03 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 0.63 Pain Relevance 0.05

General Comments

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