INT173091

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Context Info
Confidence 0.55
First Reported 2003
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.39
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (KDR) cytoplasmic membrane-bounded vesicle (KDR) plasma membrane (KDR)
nucleus (KDR) cytoplasm (KDR)
Anatomy Link Frequency
TFK-1 1
AsPC-1 1
KDR (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 92.00 High High
cytokine 10 84.08 Quite High
cva 50 80.40 Quite High
Hippocampus 10 76.48 Quite High
Neurotransmitter 8 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
Bile 6 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 82 98.68 Very High Very High Very High
Cholangiocarcinoma 74 96.04 Very High Very High Very High
Pancreatitis 3 92.00 High High
Cv General 4 Under Development 41 80.40 Quite High
Cancer 103 62.80 Quite High
Malignant Neoplastic Disease 9 56.72 Quite High
Hypersensitivity 1 54.52 Quite High
Hypoxia 50 50.00 Quite Low
Apoptosis 16 40.72 Quite Low
Recurrence 3 31.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VEGF and VEGFR were also demonstrated in human pancreatic cancer cell lines, although, in contrast to the Itakura et al study, no VEGFR mRNA was detected in cultured Capan-1 cells (VEGFR-1 mRNA-positive cells were AsPC-1, Dan-G, and PANC-1; VEGFR-2 mRNA-positive cells were AsPC-1 and Dan-G) [83].
Neg (no) Transcription (detected) of VEGFR in AsPC-1 associated with pancreatic cancer
1) Confidence 0.55 Published 2003 Journal Mol Cancer Section Body Doc Link PMC150383 Disease Relevance 0.72 Pain Relevance 0.09
In addition to growth factors, the RT-PCR study has demonstrated that both primary human MSCs and B10 cells express mRNA for VEGFR, CXCR4 and c-kit, cellular receptors known for close involvement in cellular migration (Figure 10).
Transcription (express) of VEGFR
2) Confidence 0.23 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2092394 Disease Relevance 0.20 Pain Relevance 0.18
VEGFR2 was found in EGI-1, HuH28 and OZ but not in TFK-1.
Neg (not) Transcription (found) of VEGFR2 in TFK-1
3) Confidence 0.18 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2896958 Disease Relevance 0.47 Pain Relevance 0

General Comments

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